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Protein

Pyrimidine-specific ribonucleoside hydrolase RihA

Gene

rihA

Organism
Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei240 – 2401UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciSENT295319:GJBZ-2079-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrimidine-specific ribonucleoside hydrolase RihAUniRule annotation (EC:3.2.-.-UniRule annotation)
Alternative name(s):
Cytidine/uridine-specific hydrolaseUniRule annotation
Gene namesi
Name:rihAUniRule annotation
Ordered Locus Names:SPA2079
OrganismiSalmonella paratyphi A (strain ATCC 9150 / SARB42)
Taxonomic identifieri295319 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000008185 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 311311Pyrimidine-specific ribonucleoside hydrolase RihAPRO_0000206818Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ5PM78.
SMRiQ5PM78. Positions 2-311.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the IUNH family. RihA subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218839.
KOiK01250.
OMAiIRELVMM.

Family and domain databases

Gene3Di3.90.245.10. 1 hit.
HAMAPiMF_01431. Pyrim_hydro_RihA. 1 hit.
InterProiIPR015910. I/U_nuclsd_hydro_CS.
IPR023186. Inosine/uridine_hydrolase.
IPR001910. Inosine/uridine_hydrolase_dom.
IPR022975. Pyrim_hydro_RihA.
[Graphical view]
PANTHERiPTHR12304. PTHR12304. 1 hit.
PfamiPF01156. IU_nuc_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53590. SSF53590. 1 hit.
PROSITEiPS01247. IUNH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5PM78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALPIIIDCD PGHDDAIALV LALASPELEV KAITSSAGNQ TPEKTLRNVL
60 70 80 90 100
RMLTLLKRPD IPVAGGAVKP LMRELIIADN VHGESGLDGP ALPEPSFAPQ
110 120 130 140 150
SGTAVELMAK TLRESSQPVT IVSTGPQTNV ALLLNSHPEL HAKIARIVIM
160 170 180 190 200
GGAMGLGNWT PAAEFNIYVD PEAAEIVFQS GIPVVMAGLN VTHKAQIHAA
210 220 230 240 250
DIERFRAIGN PISTIVAELL DFFMEYHKDE KWGFVGAPLH DPCTIAWLLK
260 270 280 290 300
PEIFTTVERW VGVETQGKYT QGMTVVDYYF LTGNKPNATV MVDVDRQGFV
310
DLLAERLQYY A
Length:311
Mass (Da):33,744
Last modified:January 4, 2005 - v1
Checksum:i2C310A7990C4F981
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000026 Genomic DNA. Translation: AAV77973.1.
RefSeqiWP_001207427.1. NC_006511.1.

Genome annotation databases

EnsemblBacteriaiAAV77973; AAV77973; SPA2079.
KEGGispt:SPA2079.
PATRICi32353597. VBISalEnt134188_2210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000026 Genomic DNA. Translation: AAV77973.1.
RefSeqiWP_001207427.1. NC_006511.1.

3D structure databases

ProteinModelPortaliQ5PM78.
SMRiQ5PM78. Positions 2-311.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV77973; AAV77973; SPA2079.
KEGGispt:SPA2079.
PATRICi32353597. VBISalEnt134188_2210.

Phylogenomic databases

HOGENOMiHOG000218839.
KOiK01250.
OMAiIRELVMM.

Enzyme and pathway databases

BioCyciSENT295319:GJBZ-2079-MONOMER.

Family and domain databases

Gene3Di3.90.245.10. 1 hit.
HAMAPiMF_01431. Pyrim_hydro_RihA. 1 hit.
InterProiIPR015910. I/U_nuclsd_hydro_CS.
IPR023186. Inosine/uridine_hydrolase.
IPR001910. Inosine/uridine_hydrolase_dom.
IPR022975. Pyrim_hydro_RihA.
[Graphical view]
PANTHERiPTHR12304. PTHR12304. 1 hit.
PfamiPF01156. IU_nuc_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53590. SSF53590. 1 hit.
PROSITEiPS01247. IUNH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRIHA_SALPA
AccessioniPrimary (citable) accession number: Q5PM78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 4, 2005
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.