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Q5PJB6 (Q5PJB6_SALPA) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ornithine carbamoyltransferase HAMAP-Rule MF_01109
Short name=OTCase HAMAP-Rule MF_01109
EC=2.1.3.3 HAMAP-Rule MF_01109
Gene names
Name:argI HAMAP-Rule MF_01109 EMBL AAV80003.1
Ordered Locus Names:SPA4269
OrganismSalmonella paratyphi A (strain ATCC 9150 / SARB42) [Complete proteome] [HAMAP]
Taxonomic identifier295319 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella ›

Protein attributes

Sequence length334 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. HAMAP-Rule MF_01109 SAAS SAAS002292

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 1/3. HAMAP-Rule MF_01109

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01109 SAAS SAAS002292.

Sequence similarities

Belongs to the ATCase/OTCase family. HAMAP-Rule MF_01109 RuleBase RU003634

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region56 – 605Carbamoyl phosphate binding By similarity HAMAP-Rule MF_01109
Region273 – 2764Ornithine binding By similarity HAMAP-Rule MF_01109

Sites

Binding site1071Carbamoyl phosphate By similarity HAMAP-Rule MF_01109
Binding site1341Carbamoyl phosphate By similarity HAMAP-Rule MF_01109
Site311Important for structural integrity By similarity HAMAP-Rule MF_01109
Site1471Important for structural integrity By similarity HAMAP-Rule MF_01109

Sequences

Sequence LengthMass (Da)Tools
Q5PJB6 [UniParc].

Last modified January 4, 2005. Version 1.
Checksum: EF37A456A08BE0B4

FASTA33436,741
        10         20         30         40         50         60 
MSTFYQKPFL KLLDFTASEL TALLQLAAKL KADKKNGKEE QKLVGKNIAL IFEKDSTRTR 

        70         80         90        100        110        120 
CSFEVAAYDQ GARVTYLGSS GSQIGHKESI KDTARVLGRM FDGIQYRGYG QEIVETLAEY 

       130        140        150        160        170        180 
SGVPVWNGLT DEYHPTQLLA DLLTMQEHLP GKAFNEMTLV YAGDARNNMG NSMLEAAALT 

       190        200        210        220        230        240 
GLDLRLVAPK ACWPQAALVA ECSAMAKKNG GAITLTEDIA SGVKGADFIY TDVWVSMGEP 

       250        260        270        280        290        300 
KEKWAERIAL LRDYQVNSQM MALTGNPQVK FLHCLPAFHD DETTLGKKMA EEYGLHGGME 

       310        320        330 
VTDEVFESAA SIVFDEAENR MHTIKAVMVA TLSK

« Hide

References

[1]"Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid."
McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S., Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R., Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F. expand/collapse author list , Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W., Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M., Warren W., Florea L., Spieth J., Wilson R.K.
Nat. Genet. 36:1268-1274(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 9150 / SARB42.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000026 Genomic DNA. Translation: AAV80003.1.
RefSeqYP_153315.1. NC_006511.1.

3D structure databases

ProteinModelPortalQ5PJB6.
SMRQ5PJB6. Positions 2-334.
ModBaseSearch...

Protein-protein interaction databases

STRING295319.SPA4269.

Proteomic databases

PRIDEQ5PJB6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAV80003; AAV80003; SPA4269.
GeneID3178178.
KEGGspt:SPA4269.
PATRIC32358362. VBISalEnt134188_4527.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000022686.
KOK00611.
OMARLMDFTP.
ProtClustDBPRK03515.

Enzyme and pathway databases

BioCycSENT295319:GJBZ-4263-MONOMER.
UniPathwayUPA00068; UER00112.

Family and domain databases

HAMAPMF_01109. OTCase.
InterProIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. Orn_carbamltrans.
[Graphical view]
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMSSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMsTIGR00658. orni_carb_tr. 1 hit.
PROSITEPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5PJB6_SALPA
AccessionPrimary (citable) accession number: Q5PJB6
Entry history
Integrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info