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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:SPA0355
OrganismiSalmonella paratyphi A (strain ATCC 9150 / SARB42)
Taxonomic identifieri295319 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000008185 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002736831 – 449Exodeoxyribonuclease 7 large subunitAdd BLAST449

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ5PI54.
SMRiQ5PI54.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229265.
KOiK03601.
OMAiNARRRWP.

Family and domain databases

CDDicd04489. ExoVII_LU_OBF. 1 hit.
HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiView protein in InterPro
IPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
PANTHERiPTHR30008:SF1. PTHR30008:SF1. 1 hit.
PfamiView protein in Pfam
PF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5PI54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSSQTSSIF TVSRLNQTVR LLLEQEMGQV WISGEISNFT QPASGHWYFT
60 70 80 90 100
LKDDTAQVRC AMFRNSNRRV TFRPQHGQQV LVRANITLYE PRGDYQVIAE
110 120 130 140 150
SMQPAGEGLL QQKYEQLKAK LQAEGLFDQQ HKQPLPSPAH CVGVITSKTG
160 170 180 190 200
AALHDILHVL KRRDPSLPVI IYPTAVQGDD APGQIVRAIE LANARGECDV
210 220 230 240 250
LIVGRGGGSL EDLWSFNDER VARAIFASRI PVVSAVGHET DVTIADFVAD
260 270 280 290 300
LRAPTPSAAA EIVSRNQQEL LRQIQSAQQR LGMAMDYYLA NRSRRFTQIF
310 320 330 340 350
HRLQQQHPQL RLARQQTALE RLRQRMGFAL EARIKQANQR QQRVSQRLSQ
360 370 380 390 400
QNPQPRIHRA QSRIQQLEYR LTENIRSRLS EQRERFGNAV THLEAVSPLA
410 420 430 440
TLARGYTVST TTDGKVLKKI KQVNAGDIMT TRLEDGWLES EVKSVTPGT
Length:449
Mass (Da):50,639
Last modified:January 4, 2005 - v1
Checksum:i9760406D8BE46C3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000026 Genomic DNA. Translation: AAV76369.1.
RefSeqiWP_000953178.1. NC_006511.1.

Genome annotation databases

EnsemblBacteriaiAAV76369; AAV76369; SPA0355.
KEGGispt:SPA0355.

Similar proteinsi

Entry informationi

Entry nameiEX7L_SALPA
AccessioniPrimary (citable) accession number: Q5PI54
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: January 4, 2005
Last modified: September 27, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families