Reviewed, UniProtKB/Swiss-Prot Q5PCU4 (TAL2_SALPA)

Names and origin

Protein names

Recommended name:
    Transaldolase 2
    EC=2.2.1.2

Gene names

Name:	tal2
Ordered Locus Names:	SPA0396

Organism

Salmonella paratyphi A [Complete proteome] [HAMAP]

Taxonomic identifier

54388 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	316 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity.
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00492
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transaldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 316	316	Transaldolase 2 HAMAP MF_00492		PRO_0000230970
Sites
	Active site	131	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5PCU4-1 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: D7F9B77FDAFD5D15	FASTA	316	35,538
	10 20 30 40 50 60 MNQLDGIKQF TTVVADSGDI ESIRHYQPQD ATTNPSLLLK AAGLEQYGHL IEDAIAWGKK 70 80 90 100 110 120 HGGTQEQQVA AASDKLAVNF GAEILKSIPG RVSTEVDARL SFDKEKSIEK ARHLVGLYQQ 130 140 150 160 170 180 QGIDKSRILI KLAATWEGIR AAGQLEKEGI NCNLTLLFSF AQARACAEAG VYLISPFVGR 190 200 210 220 230 240 IYDWYQARSP LEPYVVEEDP GVKSVRNIYD YFKQHRYETI VMGASFRRTE QILALTGCDR 250 260 270 280 290 300 LTISPNLLKE LKEKEEPVIR KLVPSSQMFH RPTSMTEAEF RWEHNQDAMA VEKLSEGIRL 310 FAVDQRKLED LLAAKL

References

[1]

"Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid." McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S., Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R., Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F. , Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W., Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M., Warren W., Florea L., Spieth J., Wilson R.K. Nat. Genet. 36:1268-1274(2004) [PubMed: 15531882] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 9150 / SARB42.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000026 Genomic DNA. Translation: AAV76407.1.
RefSeq	YP_149719.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3176147.
GenomeReviews	Gene locus SPA0396 in contig CP000026_GR.
KEGG	spt:SPA0396.
NMPDR	fig|295319.3.peg.1716.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5PCU4.
OMA	GCEILAI.
Enzyme and pathway databases
BioCyc	SENT295319:SPA0396-MON.
Family and domain databases
HAMAP	MF_00492. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_AB. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10683. Transaldolase. 1 hit. PTHR10683:SF3. Transaldolase_AB. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. talAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL2_SALPA

Accession

Primary (citable) accession number: Q5PCU4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	January 4, 2005
Last modified:	November 3, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)