Reviewed, UniProtKB/Swiss-Prot Q5PBP3 (DCD_ANAMM)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	AM147

Organism

Anaplasma marginale (strain St. Maries) [Complete proteome] [HAMAP]

Taxonomic identifier

234826 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Anaplasma

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 185	185	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009676

Sequences

	Sequence		Length	Mass (Da)
	Q5PBP3-1 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: CC356B6E1C9D566D	FASTA	185	20,573
	10 20 30 40 50 60 MSAMPDHWIK EKALKEGMIS PFVDHKEEAG VLSYGLSSYG YDARVDSKFK IFANTHSSIV 70 80 90 100 110 120 DPKNFPQDSF IDKETDVCIM PPNSFMLAKT VEYFRIPKDV IVICVGKSTY ARCGIVVSVT 130 140 150 160 170 180 PLEPGWEGYV TLEFSNTAPL PVKVYAFEGA CQFIFLAGNE RCSISYDQVN GKYMRQGGVT LPIVS

References

[1]

"Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins." Brayton K.A., Kappmeyer L.S., Herndon D.R., Dark M.J., Tibbals D.L., Palmer G.H., McGuire T.C., Knowles D.P. Jr. Proc. Natl. Acad. Sci. U.S.A. 102:844-849(2005) [PubMed: 15618402] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000030 Genomic DNA. Translation: AAV86286.1.
RefSeq	YP_153541.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5PBP3.
Genome annotation databases
GeneID	3171480.
GenomeReviews	Gene locus AM147 in contig CP000030_GR.
KEGG	ama:AM147.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5PBP3.
OMA	CAQVLFF.
Enzyme and pathway databases
BioCyc	AMAR234826:AM147-MON.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_ANAMM

Accession

Primary (citable) accession number: Q5PBP3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 4, 2005
Last modified:	November 3, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)