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Q5PAR7 (FENR_ANAMM) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:AM617
OrganismAnaplasma marginale (strain St. Maries) [Complete proteome] [HAMAP]
Taxonomic identifier234826 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Anaplasma

Protein attributes

Sequence length329 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Sequence caution

The sequence AAV86613.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 329329Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364782

Sites

Binding site281FAD By similarity
Binding site361FAD By similarity
Binding site411FAD By similarity
Binding site811FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1151FAD; via amide nitrogen By similarity
Binding site2821FAD By similarity
Binding site3231FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5PAR7 [UniParc].

Last modified March 3, 2009. Version 2.
Checksum: 2DF62F042E704294

FASTA32935,705
        10         20         30         40         50         60 
MAIIGAGPVG LFTVFQAGML GMSACVIDAL SEVGGQCAVL YPEKPIYDIP AYPVTLARDL 

        70         80         90        100        110        120 
VNNLKRQADP FKPTYLLGHT AEQVLEEGEH FVVVTDKKVG VRCRAIVIAA GSGGFGPNRP 

       130        140        150        160        170        180 
PLDGITEYED KSVFYHVSDV SRFRGKRVVI AGGGDSAADW AVSLSEVADS VHVIHRRHSF 

       190        200        210        220        230        240 
RCAPNTLRNL ESLAERGQIK LLVPYQLAGL AGSDGMLNGV IIRNISSKEE TRIDADFLLP 

       250        260        270        280        290        300 
FFGISAKLGP IANWGLGVES FYIPIDQSTC RTARTRIYAV GDVAHYQGKL KLILVGFSES 

       310        320 
ALACHDIYKV LFPETPLNFQ YSTSKKMPC

« Hide

References

[1]"Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins."
Brayton K.A., Kappmeyer L.S., Herndon D.R., Dark M.J., Tibbals D.L., Palmer G.H., McGuire T.C., Knowles D.P. Jr.
Proc. Natl. Acad. Sci. U.S.A. 102:844-849(2005) [PubMed: 15618402] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: St. Maries.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000030 Genomic DNA. Translation: AAV86613.1. Different initiation.
RefSeqYP_153868.1. NC_004842.2.

3D structure databases

ProteinModelPortalQ5PAR7.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5PAR7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3171421.
GenomeReviewsGene locus AM617 in contig CP000030_GR.
KEGGama:AM617.
PATRIC20947245. VBIAnaMar46146_0541.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0492.
HOGENOMHBG669726.
OMAFQVFELG.
ProtClustDBCLSK749573.

Enzyme and pathway databases

BioCycAMAR234826:AM617-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_ANAMM
AccessionPrimary (citable) accession number: Q5PAR7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: March 3, 2009
Last modified: January 25, 2012
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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