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Q5PAM4

- SYR_ANAMM

UniProt

Q5PAM4 - SYR_ANAMM

Protein

Arginine--tRNA ligase

Gene

argS

Organism
Anaplasma marginale (strain St. Maries)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (04 Jan 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

    GO - Molecular functioni

    1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
    2. ATP binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
    Alternative name(s):
    Arginyl-tRNA synthetaseUniRule annotation
    Short name:
    ArgRSUniRule annotation
    Gene namesi
    Name:argSUniRule annotation
    Ordered Locus Names:AM678
    OrganismiAnaplasma marginale (strain St. Maries)
    Taxonomic identifieri234826 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeAnaplasma
    ProteomesiUP000006557: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 579579Arginine--tRNA ligasePRO_0000241976Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi234826.AM678.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5PAM4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi136 – 14611"HIGH" regionAdd
    BLAST

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0018.
    HOGENOMiHOG000247214.
    KOiK01887.
    OMAiLCNVLAK.
    OrthoDBiEOG6JB13C.

    Family and domain databases

    Gene3Di1.10.730.10. 1 hit.
    3.30.1360.70. 1 hit.
    3.40.50.620. 1 hit.
    HAMAPiMF_00123. Arg_tRNA_synth.
    InterProiIPR001412. aa-tRNA-synth_I_CS.
    IPR001278. Arg-tRNA-ligase.
    IPR005148. Arg-tRNA-synth_N.
    IPR008909. DALR_anticod-bd.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    [Graphical view]
    PANTHERiPTHR11956. PTHR11956. 1 hit.
    PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
    PF05746. DALR_1. 1 hit.
    PF00750. tRNA-synt_1d. 1 hit.
    [Graphical view]
    PRINTSiPR01038. TRNASYNTHARG.
    SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
    SM00836. DALR_1. 1 hit.
    [Graphical view]
    SUPFAMiSSF47323. SSF47323. 1 hit.
    SSF55190. SSF55190. 1 hit.
    TIGRFAMsiTIGR00456. argS. 1 hit.
    PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5PAM4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVSAGSTINL FGNFRCIVIQ KIGELWGGEV TDSLLHKLIV APPTEDRHGD    50
    VYTNAALVVG KFKRKNPMEI AEHLRQALAE VEGVDSVDVV PPGFVNLKCS 100
    NEVWYSAIRD INKAGKDYGA VNLGQGQKVN VEFVSANPTG PLHIGHARGA 150
    VFGDVLSNLL AWVGYDVTRE YYVNDAGGQI NTLVESVYLR YKEALGEQVT 200
    IGEGLYPGEY LKPIAKALVE KHGDKLLASE DRTAVIREFA LKSILDLIRE 250
    DMALLGVKHD VFTYEADLQR SRTVEKCVEF LQQKGMLYYG TLERPRGVEE 300
    EAAWQAREQL LFRSTDFGDD SDRALQKEDG SWTYFAGDIA YHFDKISRGF 350
    HDMILGLGFD HKGYVSRLKA AVHALSDGKA TIDVKLHNMV NFLENGVPVK 400
    MSKRRGEFLT ARDVVEEVGK DVARFIMMTR KNDVVLDFDF AKAKEQSKDS 450
    QIFYIQYAHA RACSLMRNAP TLLPIEDVDF SRVSSAPEIA LIKLLVRWPN 500
    IVESSAVNHE PHRIAFYLLE VAEAFHVLWG HGSRSVDMRF IVEGDIATTS 550
    ARIYLVKVVA LVISLGLSIF SIAPMEEMR 579
    Length:579
    Mass (Da):64,676
    Last modified:January 4, 2005 - v1
    Checksum:i015D7CDA3EE81DD0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000030 Genomic DNA. Translation: AAV86656.1.
    RefSeqiYP_153911.1. NC_004842.2.

    Genome annotation databases

    EnsemblBacteriaiAAV86656; AAV86656; AM678.
    GeneIDi3171804.
    KEGGiama:AM678.
    PATRICi20947351. VBIAnaMar46146_0592.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000030 Genomic DNA. Translation: AAV86656.1 .
    RefSeqi YP_153911.1. NC_004842.2.

    3D structure databases

    ProteinModelPortali Q5PAM4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 234826.AM678.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAV86656 ; AAV86656 ; AM678 .
    GeneIDi 3171804.
    KEGGi ama:AM678.
    PATRICi 20947351. VBIAnaMar46146_0592.

    Phylogenomic databases

    eggNOGi COG0018.
    HOGENOMi HOG000247214.
    KOi K01887.
    OMAi LCNVLAK.
    OrthoDBi EOG6JB13C.

    Family and domain databases

    Gene3Di 1.10.730.10. 1 hit.
    3.30.1360.70. 1 hit.
    3.40.50.620. 1 hit.
    HAMAPi MF_00123. Arg_tRNA_synth.
    InterProi IPR001412. aa-tRNA-synth_I_CS.
    IPR001278. Arg-tRNA-ligase.
    IPR005148. Arg-tRNA-synth_N.
    IPR008909. DALR_anticod-bd.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    [Graphical view ]
    PANTHERi PTHR11956. PTHR11956. 1 hit.
    Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
    PF05746. DALR_1. 1 hit.
    PF00750. tRNA-synt_1d. 1 hit.
    [Graphical view ]
    PRINTSi PR01038. TRNASYNTHARG.
    SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
    SM00836. DALR_1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47323. SSF47323. 1 hit.
    SSF55190. SSF55190. 1 hit.
    TIGRFAMsi TIGR00456. argS. 1 hit.
    PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins."
      Brayton K.A., Kappmeyer L.S., Herndon D.R., Dark M.J., Tibbals D.L., Palmer G.H., McGuire T.C., Knowles D.P. Jr.
      Proc. Natl. Acad. Sci. U.S.A. 102:844-849(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: St. Maries.

    Entry informationi

    Entry nameiSYR_ANAMM
    AccessioniPrimary (citable) accession number: Q5PAM4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: January 4, 2005
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3