Reviewed, UniProtKB/Swiss-Prot Q5P905 (PHS_AZOSE)

Names and origin

Protein names

Recommended name:
    Putative pterin-4-alpha-carbinolamine dehydratase
      Short name=PHS
    EC=4.2.1.96
Alternative name(s):
    4-alpha-hydroxy-tetrahydropterin dehydratase
    Pterin carbinolamine dehydratase
      Short name=PCD

Gene names

Ordered Locus Names:	AZOSEA00820
ORF Names:	ebB5

Organism

Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) [Complete proteome] [HAMAP]

Taxonomic identifier

76114 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Aromatoleum

Protein attributes

Sequence length	112 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 112	112	Putative pterin-4-alpha-carbinolamine dehydratase HAMAP MF_00434		PRO_0000231440

Sequences

	Sequence		Length	Mass (Da)
	Q5P905-1 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: 5C97F080F49ED348	FASTA	112	12,521
	10 20 30 40 50 60 MSDELQSRTC TPCRGDVPPM TKAEAKRQLA QTPAWTLSDD GRCIERSFTF DDFKDAMSFV 70 80 90 100 110 AKLGELAETE GHHPDICFGW GWARVTWQTK KINGLHDNDF IMAAKTDGLA PT

References

[1]	"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1." Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R. Arch. Microbiol. 183:27-36(2005) [PubMed: 15551059] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR555306 Genomic DNA. Translation: CAI06204.1.
RefSeq	YP_157105.1.
3D structure databases
SMR	Q5P905. Positions 16-111.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5P905.
Genome annotation databases
GeneID	3182339.
GenomeReviews	Gene locus AZOSEA00820 in contig CR555306_GR.
KEGG	eba:ebB5.
NMPDR	fig|76114.4.peg.163.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2154.
HOGENOM	HBG705804.
OMA	ILTEWGK.
Enzyme and pathway databases
BioCyc	ASP76114:EBB5-MONOMER.
Family and domain databases
HAMAP	MF_00434. Pterin_4_alpha. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHS_AZOSE

Accession

Primary (citable) accession number: Q5P905

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	January 4, 2005
Last modified:	January 19, 2010
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)