Q5P8D4 (GLK_AROAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucokinase
EC=2.7.1.2

Alternative name(s):
Glucose kinase

Gene names

Name:	glk
Ordered Locus Names:	AZOSEA03030
ORF Names:	ebA584

Organism

Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) [Complete proteome] [HAMAP]

Taxonomic identifier

76114 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Aromatoleum › Aromatoleum aromaticum

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the bacterial glucokinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP glucokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	Glucokinase HAMAP-Rule MF_00524		PRO_0000268767
Regions
	Nucleotide binding	14 – 19	6	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5P8D4 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: 128A96AE9756B039	FASTA	331	34,624
	10 20 30 40 50 60 MPTGCSDTYP RLIGDIGGTH ARFAVIDSPG SPPTRFRTLC CDDHAGLLEA VQAYLLLERG 70 80 90 100 110 120 LAGPRVAAFG IANPVEGDRV RMTNHDWSFS IEQLRIELGL ARLVVLNDFT ALALSLPRLQ 130 140 150 160 170 180 AGERRQIGGG NECAGRPVAL IGPGTGLGVS GLVRCGNGYA PLEGEGGHVT LAASTPREAE 190 200 210 220 230 240 LIAVLAARFD HVSAERALSG PGLIALHDAI RQLAGAPPLA LEADEISARA MAASCPWCAE 250 260 270 280 290 300 ALQVFCGMLG SVAGDLALTL GAFGGVYIGG GIVPKLGDFF DRSDFRRRFE QKGRFSEYLA 310 320 330 RIPCYVILAE YPALLGAATA LDNALAGETG T

References

[1]

"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1." Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R. Arch. Microbiol. 183:27-36(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: EbN1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR555306 Genomic DNA. Translation: CAI06425.1.
RefSeq	YP_157326.1. NC_006513.1.
3D structure databases
HSSP	HSSP built from PDB template 1SZ2 based on UniProtKB P0A6V8.
ProteinModelPortal	Q5P8D4.
ModBase	Search...
Protein-protein interaction databases
STRING	76114.ebA584.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAI06425; CAI06425; ebA584.
GeneID	3179143.
KEGG	eba:ebA584.
PATRIC	20966639. VBIAroAro98752_0296.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0837.
HOGENOM	HOG000274469.
KO	K00845.
OMA	FADKGCM.
ProtClustDB	PRK00292.
Enzyme and pathway databases
BioCyc	AARO76114:GJTA-306-MONOMER.
Family and domain databases
HAMAP	MF_00524. Glucokinase.
InterPro	IPR003836. Glucokinase. [Graphical view]
Pfam	PF02685. Glucokinase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00749. glk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLK_AROAE

Accession

Primary (citable) accession number: Q5P8D4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	January 4, 2005
Last modified:	May 1, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program