Reviewed, UniProtKB/Swiss-Prot Q5P832 (SURE_AZOSE)

Names and origin

Protein names

Recommended name:
    5'-nucleotidase surE
    EC=3.1.3.5
Alternative name(s):
    Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	AZOSEA04070
ORF Names:	ebA782

Organism

Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) [Complete proteome] [HAMAP]

Taxonomic identifier

76114 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Aromatoleum

Protein attributes

Sequence length	247 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity.
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 247	247	5'-nucleotidase surE HAMAP MF_00060		PRO_0000235591
Sites
	Metal binding	8	1	Divalent metal cation By similarity
	Metal binding	9	1	Divalent metal cation By similarity
	Metal binding	39	1	Divalent metal cation By similarity
	Metal binding	91	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5P832-1 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: 827936CF487CFBA2	FASTA	247	26,261
	10 20 30 40 50 60 MRILVSNDDG YFAPGIAALA EALQEVGDVT VVAPERDRSA ASNSLTLDRP LSLRRAANGF 70 80 90 100 110 120 HFVNGTPTDC VHLAVTGMLD HLPDMVVSGV NHGANMGDDT IYSGTVAAAT EGFLLGVPAI 130 140 150 160 170 180 AVSLVSKAAT DFSAAARVAR DLAERFTRIP FQHPVLLNVN VPDRPYEELR GLRVTRLGKR 190 200 210 220 230 240 HKAEPVIRSV TPRNETVYWV GAAGQAADAG EGTDFQAVAE GFVSVTPLQI DLTHNGLIPS VAEWIGR

References

[1]	"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1." Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R. Arch. Microbiol. 183:27-36(2005) [PubMed: 15551059] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR555306 Genomic DNA. Translation: CAI06529.1.
RefSeq	YP_157430.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5P832.
Genome annotation databases
GeneID	3181543.
GenomeReviews	Gene locus AZOSEA04070 in contig CR555306_GR.
KEGG	eba:ebA782.
NMPDR	fig|76114.4.peg.1156.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5P832.
OMA	NLNIPPC.
Enzyme and pathway databases
BioCyc	ASP76114:EBA782-MON.
Family and domain databases
HAMAP	MF_00060. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
ProDom	PD005378. SurE. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00087. surE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_AZOSE

Accession

Primary (citable) accession number: Q5P832

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	January 4, 2005
Last modified:	November 3, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)