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Q5P804 (Q5P804_AROAE) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL CAI06557.1
Ordered Locus Names:AZOSEA04350
ORF Names:ebA829 EMBL CAI06557.1
OrganismAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) [Complete proteome] [HAMAP]
Taxonomic identifier76114 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Aromatoleum ›

Protein attributes

Sequence length414 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
Q5P804 [UniParc].

Last modified January 4, 2005. Version 1.
Checksum: D2B91F1DC84F5807

FASTA41445,212
        10         20         30         40         50         60 
MSTSHITVPT GGQKIIPGQP IPDNPIIPFI EGDGIGVDIT PVMIKVIDAA VAKAYGGKRK 

        70         80         90        100        110        120 
IHWMEVYAGE KSTQVYGPDE WLSKETLDAL KEYSVSIKGP MTTPVGGGIR SLNVALRQEL 

       130        140        150        160        170        180 
DLYQCVRPIQ YFKGVPSPLK NPELTNMVIF RENTEDIYAG IEWQADSEQA RKVIAFLQNE 

       190        200        210        220        230        240 
MGVRKIRFPA TSGIGIKPVS VEGTQRLVRA ALKYVIDNDR KSLTIVHKGN IMKFTEGLFR 

       250        260        270        280        290        300 
DVAYELAQKE FGAQPIDGGP WCKFKNPNTG REIVVKDSIA DAFLQQILLR PAEYDVIATT 

       310        320        330        340        350        360 
NLNGDYISDA LAAQVGGIGI APGANISDQY ACFEATHGTA PKYAGLDKVN PGSLILSAEM 

       370        380        390        400        410 
MLRFMKWTEA ADLVIKGMEA AIGDKVVTYD FARLMEGAQE VSCSAFGDAM IARM

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References

[1]"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1."
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.
Arch. Microbiol. 183:27-36(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EbN1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR555306 Genomic DNA. Translation: CAI06557.1.
RefSeqYP_157458.1. NC_006513.1.

3D structure databases

ProteinModelPortalQ5P804.
SMRQ5P804. Positions 4-414.
ModBaseSearch...

Protein-protein interaction databases

STRING76114.ebA829.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI06557; CAI06557; ebA829.
GeneID3181703.
KEGGeba:ebA829.
PATRIC20966909. VBIAroAro98752_0428.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
ProtClustDBCLSK766296.

Enzyme and pathway databases

BioCycAARO76114:GJTA-441-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5P804_AROAE
AccessionPrimary (citable) accession number: Q5P804
Entry history
Integrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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