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Protein

Glutamate-ammonia-ligase adenylyltransferase

Gene

glnE

Organism
Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Adenylation and deadenylation of glutamate--ammonia ligase.UniRule annotation

Catalytic activityi

ATP + [L-glutamate:ammonia ligase (ADP-forming)]-L-tyrosine = diphosphate + [L-glutamate:ammonia ligase (ADP-forming)]-O(4)-(5'-adenylyl)-L-tyrosine.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Magnesium, Nucleotide-binding

Enzyme and pathway databases

BioCyciAARO76114:GJTA-531-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-ammonia-ligase adenylyltransferaseUniRule annotation (EC:2.7.7.42UniRule annotation)
Alternative name(s):
Glutamine-synthetase adenylyltransferase
Short name:
ATaseUniRule annotation
[Glutamate--ammonia-ligase] adenylyltransferaseUniRule annotation
Gene namesi
Name:glnEUniRule annotation
Ordered Locus Names:AZOSEA05180
ORF Names:ebA977
OrganismiAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Taxonomic identifieri76114 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum
Proteomesi
  • UP000006552 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 938938Glutamate-ammonia-ligase adenylyltransferasePRO_0000209227Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi76114.ebA977.

Structurei

3D structure databases

ProteinModelPortaliQ5P7S1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni112 – 319208GlnE 1Add
BLAST
Regioni619 – 823205GlnE 2Add
BLAST

Sequence similaritiesi

Belongs to the GlnE family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105CE6. Bacteria.
COG1391. LUCA.
HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.
OrthoDBiPOG091H0675.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5P7S1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLEADAARLK TDRLGYNPLH VLRADAATRR QEPAILTMIR SSPPMSVDSS
60 70 80 90 100
PLPEALRHAA SISRFMRRML DSRPWLAAQL AGSLGQPLDS EAMSSFLANR
110 120 130 140 150
GVDEARLRAS LRHLRSWVVC HVLTRDLNGF ADLAEVTETM TVLAEVTVRA
160 170 180 190 200
TYEVLREGLV ARYGAPLSPT GWEQELLVIG MGKLGGRELN VSSDIDLIFV
210 220 230 240 250
YPEDGDTGGN KVISNFEFFE RLGKQMIQAL ADVTEHGQVF RVDMRLRPNG
260 270 280 290 300
DSGPLVCSFD MLENYFITQG REWERYAWIK ARVLAGERYH ELEQIARPFV
310 320 330 340 350
FRKYLDFGSI NAMRALHAQI RREVTRRDRV NNIKLGPGGI REIEFTAQVF
360 370 380 390 400
QLIRGGREPG LQVRATLDVL AVLGERGILT PQTVGELAEA YDFLRRLEHR
410 420 430 440 450
LQYLDDAQTH DLPGNDEDCE CIARAMDFPD YTSFLGVLDH HRAAVSRHFD
460 470 480 490 500
HVFGDPSEEA HTLDSMWAAA RDVEQAEPIL SRLGYGDPSG AAHRLAALHG
510 520 530 540 550
SARYQQLPNH IRSRLDALMP RVVEVAAATP GPDETLARCI DLIEAISRRG
560 570 580 590 600
AYLALLQQYP QALRRVADLV GASRWAAQYL TRHPILLDEL LDDRNLEPAP
610 620 630 640 650
DWDALRAQMR DTLDTLEPDM ERQMDVMREQ HHAQVFRLLT QDIAGLLTVE
660 670 680 690 700
KLADHLSALA DLMLELALPL VWRKIKIRHR DDPAFAVIAY GKLGGKELGY
710 720 730 740 750
ASDLDIVFLF DDPAPEALEV YTRLAQRINT WLSSQTAAGI LFETDLRLRP
760 770 780 790 800
NGESGLLVTS IESFRKYQLE SAWVWEHQAL TRARFAAGDA TIGAAFERIR
810 820 830 840 850
CEVLRLPRDI AALRAEVLAM RRKMSDAHAG KSERFNLKHD AGGLVDVEFL
860 870 880 890 900
IQYLVLGHAH RYPELTGNLG NIALLRIAGE LGLIPAELAA RCGDSYRLFR
910 920 930
RLQHRQRLNG LLSLVAPDEV AAAREPVRAL WTIVFGSA
Length:938
Mass (Da):105,278
Last modified:January 4, 2005 - v1
Checksum:iC26993BA14378E57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR555306 Genomic DNA. Translation: CAI06640.1.

Genome annotation databases

EnsemblBacteriaiCAI06640; CAI06640; ebA977.
KEGGieba:ebA977.
PATRICi20967101. VBIAroAro98752_0517.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR555306 Genomic DNA. Translation: CAI06640.1.

3D structure databases

ProteinModelPortaliQ5P7S1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi76114.ebA977.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAI06640; CAI06640; ebA977.
KEGGieba:ebA977.
PATRICi20967101. VBIAroAro98752_0517.

Phylogenomic databases

eggNOGiENOG4105CE6. Bacteria.
COG1391. LUCA.
HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.
OrthoDBiPOG091H0675.

Enzyme and pathway databases

BioCyciAARO76114:GJTA-531-MONOMER.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLNE_AROAE
AccessioniPrimary (citable) accession number: Q5P7S1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: January 4, 2005
Last modified: September 7, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.