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Q5P7K8 (PGK_AROAE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:AZOSEA05810
ORF Names:ebA1103
OrganismAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) [Complete proteome] [HAMAP]
Taxonomic identifier76114 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 394394Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000057962

Regions

Nucleotide binding347 – 3504ATP By similarity
Region21 – 233Substrate binding By similarity
Region60 – 634Substrate binding By similarity

Sites

Binding site371Substrate By similarity
Binding site1151Substrate By similarity
Binding site1481Substrate By similarity
Binding site1991ATP By similarity
Binding site3211ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5P7K8 [UniParc].

Last modified January 4, 2005. Version 1.
Checksum: 8D8025D4642154AF

FASTA39441,688
        10         20         30         40         50         60 
MNVKKLADLD VAGKRVFIRA DLNVPQDEAG NIVEDTRIRA SLPSIRYCLE RSATVMVTSH 

        70         80         90        100        110        120 
LGRPTEGECR AEDTLAPIAV RLGELLGKPV RLIRDWVEGG FEVRAGEVVL LENCRCNKGE 

       130        140        150        160        170        180 
KKDNEELAKK MAALCDIYVN DAFGTAHRAE ATTHGIARFA PVACAGMLMG AEIDALTKAT 

       190        200        210        220        230        240 
ENPARPLVAI VGGAKVSTKL TILKTLAEKV DQLIVGGGIA NTFLLASGKR IGESLAEPEL 

       250        260        270        280        290        300 
VKEAQAIMDM MKARGAEVPL PVDVVVADEV SALARANRIP VDEVGPHDRI LDVGPKSSAK 

       310        320        330        340        350        360 
LAEIIAHAGT IVWNGPVGVF EHNQFAGGTK MMASAIAHSE AFCIAGGGDT LAAIAKFHIA 

       370        380        390 
QDIGYISTGG GAFLEFLEGK KLPAIAALEA RFAD 

« Hide

References

[1]"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1."
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.
Arch. Microbiol. 183:27-36(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EbN1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR555306 Genomic DNA. Translation: CAI06703.1.
RefSeqYP_157604.1. NC_006513.1.

3D structure databases

ProteinModelPortalQ5P7K8.
SMRQ5P7K8. Positions 3-392.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING76114.ebA1103.

Proteomic databases

PRIDEQ5P7K8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI06703; CAI06703; ebA1103.
GeneID3180668.
KEGGeba:ebA1103.
PATRIC20967241. VBIAroAro98752_0587.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAMSIRYID.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycAARO76114:GJTA-594-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_AROAE
AccessionPrimary (citable) accession number: Q5P7K8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: January 4, 2005
Last modified: June 11, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways