ID   HEM6_AZOSE              Reviewed;         311 AA.
AC   Q5P7I0;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   16-JUN-2009, entry version 33.
DE   RecName: Full=Coproporphyrinogen-III oxidase, aerobic;
DE            Short=Coproporphyrinogenase;
DE            Short=Coprogen oxidase;
DE            EC=1.3.3.3;
GN   Name=hemF; OrderedLocusNames=AZOSEA06090; ORFNames=ebA1156;
OS   Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC   Rhodocyclaceae; Aromatoleum.
OX   NCBI_TaxID=76114;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15551059; DOI=10.1007/s00203-004-0742-9;
RA   Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F.,
RA   Reinhardt R.;
RT   "The genome sequence of an anaerobic aromatic-degrading denitrifying
RT   bacterium, strain EbN1.";
RL   Arch. Microbiol. 183:27-36(2005).
CC   -!- CATALYTIC ACTIVITY: Coproporphyrinogen-III + O(2) + 2 H(+) =
CC       protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
CC   -!- PATHWAY: Porphyrin metabolism; protoporphyrin-IX biosynthesis;
CC       protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step
CC       1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the aerobic coproporphyrinogen-III oxidase
CC       family.
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DR   EMBL; CR555306; CAI06731.1; -; Genomic_DNA.
DR   RefSeq; YP_157632.1; -.
DR   GeneID; 3179556; -.
DR   GenomeReviews; CR555306_GR; AZOSEA06090.
DR   KEGG; eba:ebA1156; -.
DR   NMPDR; fig|76114.4.peg.1728; -.
DR   HOGENOM; Q5P7I0; -.
DR   OMA; Q5P7I0; VKAYLLD.
DR   BioCyc; ASP76114:EBA1156-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004109; F:coproporphyrinogen oxidase activity; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006779; P:porphyrin biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00333; -; 1.
DR   InterPro; IPR001260; Coprogen_oxidas.
DR   InterPro; IPR018375; Coproporphyrinogen-3_ox_CS.
DR   Gene3D; G3DSA:3.40.1500.10; Coprogen_oxidas; 1.
DR   PANTHER; PTHR10755; Coprogen_oxidas; 1.
DR   Pfam; PF01218; Coprogen_oxidas; 1.
DR   PIRSF; PIRSF000166; Coproporphyri_ox; 1.
DR   PRINTS; PR00073; COPRGNOXDASE.
DR   PROSITE; PS01021; COPROGEN_OXIDASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Oxidoreductase; Porphyrin biosynthesis.
FT   CHAIN         1    311       Coproporphyrinogen-III oxidase, aerobic.
FT                                /FTId=PRO_0000109882.
SQ   SEQUENCE   311 AA;  35220 MW;  071C7B4170074D02 CRC64;
     MGAPDSRVVR QHLLDLQSGI VAVLERFDGG RFREDAWQRP AGGGGITRVI EEGRFFERGG
     VNFSHVIGGA MPASATAHRP DLAGRTFEAM GVSLVLHPRN PYCPTVHMNV RFFIASHPEA
     AVPPPAAAPV WWFGGGMDLT PYYPYEEDVR NFHRACRAAV LPWGGEPEYR RLKEWCDRYF
     FLKHRNEPRG VGGLFFDDLG ADGKTDFDAA FGLARSVGDA FLDAYLPIIE RRRDVAYGER
     ERDFQAYRRG RYVEFNLVFD RGTLFGLQSG GRTESILMSL PPVVKWRYDW QPEPGSAEAR
     LYDEFLAPRD W
//