Reviewed, UniProtKB/Swiss-Prot Q5P7I0 (HEM6_AZOSE)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen 3 oxidase, aerobic
    EC=1.3.3.3
Alternative name(s):
    Coproporphyrinogen III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase

Gene names

Name:	hemF
Ordered Locus Names:	AZOSEA06090
ORF Names:	ebA1156

Organism

Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) [Complete proteome] [HAMAP]

Taxonomic identifier

76114 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Aromatoleum

Protein attributes

Sequence length	311 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 311	311	Coproporphyrinogen 3 oxidase, aerobic		PRO_0000109882

Sequences

	Sequence		Length	Mass (Da)
	Q5P7I0-1 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: 071C7B4170074D02	FASTA	311	35,220
	10 20 30 40 50 60 MGAPDSRVVR QHLLDLQSGI VAVLERFDGG RFREDAWQRP AGGGGITRVI EEGRFFERGG 70 80 90 100 110 120 VNFSHVIGGA MPASATAHRP DLAGRTFEAM GVSLVLHPRN PYCPTVHMNV RFFIASHPEA 130 140 150 160 170 180 AVPPPAAAPV WWFGGGMDLT PYYPYEEDVR NFHRACRAAV LPWGGEPEYR RLKEWCDRYF 190 200 210 220 230 240 FLKHRNEPRG VGGLFFDDLG ADGKTDFDAA FGLARSVGDA FLDAYLPIIE RRRDVAYGER 250 260 270 280 290 300 ERDFQAYRRG RYVEFNLVFD RGTLFGLQSG GRTESILMSL PPVVKWRYDW QPEPGSAEAR 310 LYDEFLAPRD W

References

[1]	"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1." Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R. Arch. Microbiol. 183:27-36(2005) [PubMed: 15551059] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR555306 Genomic DNA. Translation: CAI06731.1.
RefSeq	YP_157632.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3179556.
GenomeReviews	Gene locus AZOSEA06090 in contig CR555306_GR.
KEGG	eba:ebA1156.
NMPDR	fig|76114.4.peg.1728.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5P7I0.
Enzyme and pathway databases
BioCyc	ASP76114:EBA1156-MON.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_AZOSE

Accession

Primary (citable) accession number: Q5P7I0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 12, 2005
Last sequence update:	January 4, 2005
Last modified:	November 4, 2008
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)