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Q5P7H5 (CAPP_AROAE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:AZOSEA06140
ORF Names:ebA1167
OrganismAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) [Complete proteome] [HAMAP]
Taxonomic identifier76114 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum

Protein attributes

Sequence length916 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Sequence caution

The sequence CAI06736.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 916916Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_0000166579

Sites

Active site1441 By similarity
Active site5781 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5P7H5 [UniParc].

Last modified August 30, 2005. Version 2.
Checksum: 4A45C86CF16B69EC

FASTA916101,239
        10         20         30         40         50         60 
MTEDKDAPLR EDIRLLGRVL GDTVRDQHGE AAFALIERIR QTSVRFRRDD DNAARLELEG 

        70         80         90        100        110        120 
ILDALSREQT IEVVRAFSYF SHLSNIAEDQ HHIRRSRAHL IAGSAPREGS VAHALVRALA 

       130        140        150        160        170        180 
SGLPPARLAA FFDTALISPV LTAHPTEVQR KSILNCETDI AHLLDARDRM TLTPEERQES 

       190        200        210        220        230        240 
DEALRRTVLT LWQTRMLRPA KLSVVDEVAN GLSYFDATFL RELPHLYANL EDQLVSRDPA 

       250        260        270        280        290        300 
LAGLELPAFL QVGSWIGGDR DGNPFVTADV LERTLAMQAG AVLGFYLDEL HALGARLSLA 

       310        320        330        340        350        360 
LGLVTASDAL LALAARSPDH SPHRNDEPYR RAISGIYARL AATHHALLGT EPPRHPVAVA 

       370        380        390        400        410        420 
EPYAAVAELA DDLDVIHRSL VANGSAALAR GQLRRLRRAV RVFGFHLAPI DLRQNSEVHE 

       430        440        450        460        470        480 
RVVAELLATA RTGTDYATLD EAARVELLIE ELATPRPLAS PHVRYSDETE GELAIFRTAR 

       490        500        510        520        530        540 
AAHRRYGGPA IPNCIISKTD DVSDLLELAL LLKEAGLLRP HERALDVNIV PLFETIEDLA 

       550        560        570        580        590        600 
NAPSVMDRLF ALPGYMNLLA ASRDRTHEVM LGYSDSNKDG GFLTSGWALY KAEIGLIEVF 

       610        620        630        640        650        660 
ARHGIRLRLF HGRGGSVGRG GGPSYEAILA QPGGAVQGQI RLTEQGEVIA AKYGNPEVGR 

       670        680        690        700        710        720 
RNLEVIVAAT LEASLLADRA PAPRVEFLDT MQALSDVAFA AYRGLVYDTE GFERYFWEST 

       730        740        750        760        770        780 
VISEIAELNI GSRPASRKKG TRIEDLRAIP WVFSWSQCRL MLPGWFGFGS AVKTWLAAHA 

       790        800        810        820        830        840 
DDGIARLQAM HREWSFFAAL LSNMDMVLAK TDLAIASRYA GLVKDVNLRD AIFERIRNEW 

       850        860        870        880        890        900 
HDTVDALLAI TGQRELLDGN PLLKRSIRNR FPYLDPLNHV QVELLRRHRE THDDARIRLG 

       910 
IHISINGIAA GLRNSG 

« Hide

References

[1]"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1."
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.
Arch. Microbiol. 183:27-36(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EbN1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR555306 Genomic DNA. Translation: CAI06736.1. Different initiation.
RefSeqYP_157637.1. NC_006513.1.

3D structure databases

ProteinModelPortalQ5P7H5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING76114.ebA1167.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI06736; CAI06736; ebA1167.
GeneID3179678.
KEGGeba:ebA1167.
PATRIC20967315. VBIAroAro98752_0624.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238647.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycAARO76114:GJTA-627-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_AROAE
AccessionPrimary (citable) accession number: Q5P7H5
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: August 30, 2005
Last modified: February 19, 2014
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families