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Q5P6K4 (UPPP_AROAE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:upk
Ordered Locus Names:AZOSEA09320
ORF Names:ebA1726
OrganismAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) [Complete proteome] [HAMAP]
Taxonomic identifier76114 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum

Protein attributes

Sequence length274 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 274274Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151084

Regions

Transmembrane4 – 2421Helical; Potential
Transmembrane41 – 6121Helical; Potential
Transmembrane83 – 10321Helical; Potential
Transmembrane108 – 12821Helical; Potential
Transmembrane184 – 20421Helical; Potential
Transmembrane218 – 23821Helical; Potential
Transmembrane246 – 26621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q5P6K4 [UniParc].

Last modified January 4, 2005. Version 1.
Checksum: 399202A419562630

FASTA27430,013
        10         20         30         40         50         60 
MDLPLFVIAL ILGIVEGLTE FLPISSTGHL IIIGDLLGYN DATSKVFKIV IQFAAILAVC 

        70         80         90        100        110        120 
WDYRERLARV AAGVGSEPAA QRFVGLLFIG FLPAAVLGLM FHSTIKSLLF NPLTVATALV 

       130        140        150        160        170        180 
VGGVLILWLE RRAYHPRINA VDEMRWADAL KVGFAQAAAM IPGTSRSGAT ILGGLVFGLS 

       190        200        210        220        230        240 
RKAAAEFSFF LSIPTMFAAT VYDLYKNRDL LHMGDLPVFA IGFVASFFAA MFAVKAFIRF 

       250        260        270 
ISNHTFIAFA WYRIVFGLVV LATWQLELVE WSEP 

« Hide

References

[1]"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1."
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.
Arch. Microbiol. 183:27-36(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EbN1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR555306 Genomic DNA. Translation: CAI07057.1.
RefSeqYP_157958.1. NC_006513.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING76114.ebA1726.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI07057; CAI07057; ebA1726.
GeneID3183038.
KEGGeba:ebA1726.
PATRIC20967973. VBIAroAro98752_0947.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAVIYFRNE.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycAARO76114:GJTA-951-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_AROAE
AccessionPrimary (citable) accession number: Q5P6K4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: January 4, 2005
Last modified: May 14, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families