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Q5P5M2 (PYRF_AROAE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:AZOSEA12650
ORF Names:ebA2293
OrganismAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) [Complete proteome] [HAMAP]
Taxonomic identifier76114 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum

Protein attributes

Sequence length271 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 271271Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000066455

Sites

Active site951Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5P5M2 [UniParc].

Last modified January 4, 2005. Version 1.
Checksum: DBBB130385A9995B

FASTA27129,303
        10         20         30         40         50         60 
MHFMTALRAA WRTRNSLLCV GLDPDPTRFP AHLHGQPDAI FRFCSEIVDA TADLVCCFKP 

        70         80         90        100        110        120 
QIAYFAAQRA EDQLEALIAH IHARHPGTPV ILDAKRGDIG SSAGQYAVEA FERFGADAIT 

       130        140        150        160        170        180 
VNPYMGRDSV EPYLEYTDKG VILLCRTSNP GGSDLQFLDV GGGERLFERV ARLVADEWNQ 

       190        200        210        220        230        240 
SGNCSLVVGA TFPNEIARVR ELVGDLPLLV PGIGAQGGDI AATVEAGRSA DRTGLMINSS 

       250        260        270 
RAILYAGADH DFAAAARRAA LDTRDAINRH R 

« Hide

References

[1]"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1."
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.
Arch. Microbiol. 183:27-36(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EbN1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR555306 Genomic DNA. Translation: CAI07390.1.
RefSeqYP_158291.1. NC_006513.1.

3D structure databases

ProteinModelPortalQ5P5M2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING76114.ebA2293.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI07390; CAI07390; ebA2293.
GeneID3181839.
KEGGeba:ebA2293.
PATRIC20968645. VBIAroAro98752_1283.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000245747.
KOK01591.
OMAHIHARHP.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycAARO76114:GJTA-1284-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
ProtoNetSearch...

Entry information

Entry namePYRF_AROAE
AccessionPrimary (citable) accession number: Q5P5M2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: January 4, 2005
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways