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Protein

Guanylate kinase

Gene

gmk

Organism
Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 17ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAARO76114:G1GHY-1947-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:AZOSEA19690
ORF Names:ebA3494
OrganismiAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Taxonomic identifieri76114 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum
Proteomesi
  • UP000006552 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002662871 – 204Guanylate kinaseAdd BLAST204

Proteomic databases

PRIDEiQ5P3M0

Interactioni

Protein-protein interaction databases

STRINGi76114.ebA3494

Structurei

3D structure databases

ProteinModelPortaliQ5P3M0
SMRiQ5P3M0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 181Guanylate kinase-likeUniRule annotationAdd BLAST179

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037638
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5P3M0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGTLIIITA PSGAGKTTLV SGLLERDPQV NLSVSYTTRE PRPGERDGRE
60 70 80 90 100
YHFVDVATFR ALRDRGEFLE WAEVHGNYYA TSKVWLKQQI ATGRDILLEI
110 120 130 140 150
DWQGAQQVRK SFPDAVGVFI LPPSLEELEA RLRGRGTDSD DVIMRRLLGA
160 170 180 190 200
RGEMRHVGEF DYVILNNDLQ CALDDLVAVV RASRLRYANQ HERHLQYFDF

LEQD
Length:204
Mass (Da):23,259
Last modified:December 12, 2006 - v2
Checksum:iB1224686D41F06D5
GO

Sequence cautioni

The sequence CAI08094 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR555306 Genomic DNA Translation: CAI08094.1 Different initiation.
RefSeqiWP_041647120.1, NC_006513.1

Genome annotation databases

EnsemblBacteriaiCAI08094; CAI08094; ebA3494
KEGGieba:ebA3494

Similar proteinsi

Entry informationi

Entry nameiKGUA_AROAE
AccessioniPrimary (citable) accession number: Q5P3M0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: December 12, 2006
Last modified: March 28, 2018
This is version 78 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health