Reviewed, UniProtKB/Swiss-Prot Q5P3E7 (SYR_AZOSE)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	AZOSEA20420
ORF Names:	ebA3614

Organism

Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) [Complete proteome] [HAMAP]

Taxonomic identifier

76114 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Aromatoleum

Protein attributes

Sequence length	587 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 587	587	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_0000241978
Regions
	Motif	126 – 136	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q5P3E7-1 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: 5282E64F1F808A55	FASTA	587	64,854
	10 20 30 40 50 60 MSADSKVQLT ALLRAALKSI APELADTPIH LERPKQAGHG DFATNLALQL AKPLRRRPRE 70 80 90 100 110 120 LAELLLAELP RSTLVAATEV AGAGFINFTL AAGAKTAAVG TVLERGAEFG RGARNGTSVQ 130 140 150 160 170 180 LEFVSANPTG PLHVGHGRGA AYGASLAAVL DFAGSDVTRE YYINDAGRQM DILALSTWLR 190 200 210 220 230 240 YLALYGLDIP FPPNAYQGDY VVDMARAMRE GHQDRFAGFT IEQVLEGAPG LPVAERKDDE 250 260 270 280 290 300 AKTQREDHLD MLIANAKRLL GEDYHFVHGF ALNEQLGDGR DDLEEFGVHF DKWFSEKSLF 310 320 330 340 350 360 DTGLVDRAVA ELEKRGHVYL QDGAKWFRST AFGDEKDRVV QRENGLYTYF ASDIAYHLNK 370 380 390 400 410 420 YERGYDRIID IWGADHHGYI PRVKGAIAAL GLPPEKLEVA LVQFAVLYRN GQKASMSTRS 430 440 450 460 470 480 GEFVTLRELR REVGNDACRF FYVLRKSDQH LDFDLDLAKS QSNENPVYYV QYAHARVCSV 490 500 510 520 530 540 LEQWGGEAAE LRAAQLDLLG NERELALCAR LGGFPELIQN AAADHAPHQI AFYLKDLAAE 550 560 570 580 FHSWYNAERM LVDDPALRLA RLALATAVRQ VLATALALLG VSAPQSM

References

[1]	"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1." Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R. Arch. Microbiol. 183:27-36(2005) [PubMed: 15551059] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR555306 Genomic DNA. Translation: CAI08167.1.
RefSeq	YP_159068.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5P3E7.
Genome annotation databases
GeneID	3181291.
GenomeReviews	Gene locus AZOSEA20420 in contig CR555306_GR.
KEGG	eba:ebA3614.
NMPDR	fig|76114.4.peg.2355.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5P3E7.
OMA	ADHHGYV.
Enzyme and pathway databases
BioCyc	ASP76114:EBA3614-MON.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_AZOSE

Accession

Primary (citable) accession number: Q5P3E7

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	January 4, 2005
Last modified:	November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)