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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAARO76114:G1GHY-2017-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:AZOSEA20420
ORF Names:ebA3614
OrganismiAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Taxonomic identifieri76114 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum
Proteomesi
  • UP000006552 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002419781 – 587Arginine--tRNA ligaseAdd BLAST587

Proteomic databases

PRIDEiQ5P3E7

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi76114.ebA3614

Structurei

3D structure databases

ProteinModelPortaliQ5P3E7
SMRiQ5P3E7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi126 – 136"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 2 hits
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q5P3E7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSADSKVQLT ALLRAALKSI APELADTPIH LERPKQAGHG DFATNLALQL
60 70 80 90 100
AKPLRRRPRE LAELLLAELP RSTLVAATEV AGAGFINFTL AAGAKTAAVG
110 120 130 140 150
TVLERGAEFG RGARNGTSVQ LEFVSANPTG PLHVGHGRGA AYGASLAAVL
160 170 180 190 200
DFAGSDVTRE YYINDAGRQM DILALSTWLR YLALYGLDIP FPPNAYQGDY
210 220 230 240 250
VVDMARAMRE GHQDRFAGFT IEQVLEGAPG LPVAERKDDE AKTQREDHLD
260 270 280 290 300
MLIANAKRLL GEDYHFVHGF ALNEQLGDGR DDLEEFGVHF DKWFSEKSLF
310 320 330 340 350
DTGLVDRAVA ELEKRGHVYL QDGAKWFRST AFGDEKDRVV QRENGLYTYF
360 370 380 390 400
ASDIAYHLNK YERGYDRIID IWGADHHGYI PRVKGAIAAL GLPPEKLEVA
410 420 430 440 450
LVQFAVLYRN GQKASMSTRS GEFVTLRELR REVGNDACRF FYVLRKSDQH
460 470 480 490 500
LDFDLDLAKS QSNENPVYYV QYAHARVCSV LEQWGGEAAE LRAAQLDLLG
510 520 530 540 550
NERELALCAR LGGFPELIQN AAADHAPHQI AFYLKDLAAE FHSWYNAERM
560 570 580
LVDDPALRLA RLALATAVRQ VLATALALLG VSAPQSM
Length:587
Mass (Da):64,854
Last modified:January 4, 2005 - v1
Checksum:i5282E64F1F808A55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR555306 Genomic DNA Translation: CAI08167.1
RefSeqiWP_011237860.1, NC_006513.1

Genome annotation databases

EnsemblBacteriaiCAI08167; CAI08167; ebA3614
KEGGieba:ebA3614

Similar proteinsi

Entry informationi

Entry nameiSYR_AROAE
AccessioniPrimary (citable) accession number: Q5P3E7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: January 4, 2005
Last modified: May 23, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health