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Reviewed, UniProtKB/Swiss-Prot Q5P286 (ARGB_AZOSE)

Last modified February 9, 2010. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Acetylglutamate kinase
    EC=2.7.2.8
Alternative name(s):
    NAG kinase
      Short name=AGK
    N-acetyl-L-glutamate 5-phosphotransferase
Gene names
Name: argB
Ordered Locus Names: AZOSEA24530
ORF Names: ebA4330
OrganismAzoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) [Complete proteome] [HAMAP]
Taxonomic identifier76114 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum

Protein attributes

Sequence length300 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082

Subcellular location

Cytoplasm Probable HAMAP MF_00082.

Sequence similarities

Belongs to the acetylglutamate kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 300300Acetylglutamate kinase HAMAP MF_00082
PRO_0000264681

Regions

Region72 – 732Substrate binding By similarity

Sites

Binding site941Substrate By similarity
Binding site1971Substrate By similarity
Site371Transition state stabilizer By similarity
Site2571Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5P286-1 [UniParc].

Last modified January 4, 2005. Version 1.
Checksum: E1AFC1FD89D64B73

FASTA30031,740
        10         20         30         40         50         60 
MPQLPAPTDV TPARKAEILA EALPYIKRFF DKTVVIKYGG NAMTDPHLKD CFARDVVLLK 

        70         80         90        100        110        120 
LVGLNPVVVH GGGPQIETLL ARVGKKGEFI QGMRVTDAET MEVVEMVLGG QVNKEIVSLI 

       130        140        150        160        170        180 
NQHGGKAVGL TGKDASFIRA KKLLMQKEDA APGDVVDVGQ VGEITKIDPS LIAFLDQGDF 

       190        200        210        220        230        240 
IPVIAPIGVG EAGETYNINA DVVAGKLAEI LKAEKLVLLT NTPGVLDKAG KLLTGLTPHQ 

       250        260        270        280        290        300 
IDDLVADGTL SGGMLPKISS ALDAARNGVK SVHIIDGRVE HCLLLEILTD HGVGTMIKSK 

« Hide

References

[1]"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1."
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.
Arch. Microbiol. 183:27-36(2005) [PubMed: 15551059] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR555306 Genomic DNA. Translation: CAI08578.1.
RefSeqYP_159479.1.

3D structure databases

HSSPHSSP built from PDB template 2BUF based on UniProtKB Q9HTN2.
SMRQ5P286. Positions 13-300.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5P286.

Genome annotation databases

GeneID3181048.
GenomeReviewsGene locus AZOSEA24530 in contig CR555306_GR.
KEGGeba:ebA4330.
NMPDRfig|76114.4.peg.2751.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0548.
HOGENOMHBG497643.
OMAMDIVEMV.

Enzyme and pathway databases

BioCycASP76114:EBA4330-MONOMER.

Family and domain databases

HAMAPMF_00082_B. ArgB_B.
[Tree]
InterProIPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR011148. GlcNAc_kinase.
IPR001057. Glu_5kinase.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
PfamPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000728. NAGK. 1 hit.
PRINTSPR00474. GLU5KINASE.
TIGRFAMsTIGR00761. argB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameARGB_AZOSE
AccessionPrimary (citable) accession number: Q5P286
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: January 4, 2005
Last modified: February 9, 2010
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents