Q5P261 (GCP_AROAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	AZOSEA24780
ORF Names:	ebA4371

Organism

Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) [Complete proteome] [HAMAP]

Taxonomic identifier

76114 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Aromatoleum

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 342	342	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303261

Sequences

	Sequence		Length	Mass (Da)
	Q5P261 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: ACCAF162BF422CB7	FASTA	342	35,677
	10 20 30 40 50 60 MKVLGIETSC DETGVAIFDT AAGLLGHCVH TQIALHAAYG GVVPELASRD HIRRLPLLVK 70 80 90 100 110 120 QTLDAAGCEL SQLDAIAYTA GPGLAGALLV GASFAESLGL ALAVPVLPIH HLEGHLLSPL 130 140 150 160 170 180 LAADPPAFPF VALLVSGGHT QLMRVTGVGE YALLGESVDD AAGEAFDKTA KLLGLGYPGG 190 200 210 220 230 240 PQLAALAERG QTGRFRLPRP MLRSGDLDFS FSGLKTAVLN VVSAPTWRAE DVADLAADFQ 250 260 270 280 290 300 AAVVEVLCAK ALRALEQTGL ARLVVAGGVG ANRHLRERLD ASTRRKGCRV YYPEPELCTD 310 320 330 340 NGAMIAFAGA LRAAAGQRGG ETPAVRVFPR WPLAELHSPV QP

References

[1]

"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1." Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R. Arch. Microbiol. 183:27-36(2005) [PubMed: 15551059] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: EbN1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR555306 Genomic DNA. Translation: CAI08603.1.
RefSeq	YP_159504.1. NC_006513.1.
3D structure databases
ProteinModelPortal	Q5P261.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5P261.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3179237.
GenomeReviews	Gene locus AZOSEA24780 in contig CR555306_GR.
KEGG	eba:ebA4371.
NMPDR	fig|76114.4.peg.2776.
PATRIC	20971128. VBIAroAro98752_2507.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	ASP76114:EBA4371-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_AROAE

Accession

Primary (citable) accession number: Q5P261

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	January 4, 2005
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program