Reviewed, UniProtKB/Swiss-Prot Q5P236 (DCD_AZOSE)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	AZOSEA25030
ORF Names:	ebA4412

Organism

Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) [Complete proteome] [HAMAP]

Taxonomic identifier

76114 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Aromatoleum

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009680

Sequences

	Sequence		Length	Mass (Da)
	Q5P236-1 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: 6E67018AE6A67C11	FASTA	188	21,034
	10 20 30 40 50 60 MSIKSDKWIR RMAEQQGMIA PFAPELVRHN GTGKIVSYGT SSYGYDVRCA NEFKIFTNIN 70 80 90 100 110 120 STIVDPKDFD ARNFVDFVGD VCIIPPNSFA LARTVEYFRI PRNVLTVCLG KSTYARCGII 130 140 150 160 170 180 VNVTPLEPEW EGHVTLEFSN TTPLPAKIYA NEGIAQMLFF EADEVCETSY KDRGGKYLGQ TGVTLPKI

References

[1]	"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1." Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R. Arch. Microbiol. 183:27-36(2005) [PubMed: 15551059] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR555306 Genomic DNA. Translation: CAI08628.1.
RefSeq	YP_159529.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5P236.
Genome annotation databases
GeneID	3179742.
GenomeReviews	Gene locus AZOSEA25030 in contig CR555306_GR.
KEGG	eba:ebA4412.
NMPDR	fig|76114.4.peg.2800.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5P236.
OMA	CAQVLFF.
Enzyme and pathway databases
BioCyc	ASP76114:EBA4412-MON.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_AZOSE

Accession

Primary (citable) accession number: Q5P236

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 4, 2005
Last modified:	November 3, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)