Reviewed, UniProtKB/Swiss-Prot Q5P1G9 (PPNK_AZOSE)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase
      Short name=Poly(P)/ATP NAD kinase
    EC=2.7.1.23

Gene names

Name:	ppnK
Ordered Locus Names:	AZOSEA27200
ORF Names:	ebA4805

Organism

Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) [Complete proteome] [HAMAP]

Taxonomic identifier

76114 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Aromatoleum

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 300	300	Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361		PRO_0000229598

Sequences

	Sequence		Length	Mass (Da)
	Q5P1G9-1 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: E987ECF15C086D0E	FASTA	300	32,959
	10 20 30 40 50 60 MWFNPRMSKN FRVVALIGKY QSPEVAEAVL RIAEFLRVRG LDVWIEQGTA SSIGMAGQFA 70 80 90 100 110 120 VASYEEIGAQ ADLAVVLGGD GTMLNTARRL SQHGVPLVGI NQGRLGFLTD ISRDEALPKL 130 140 150 160 170 180 GEILEGRYTE ESRAMLDAEV LRAGHRVFQT LALNDVVINK GDLGRMIEFD LSIDGEFVYT 190 200 210 220 230 240 QRSDGMILAT PTGSTAYALS ANGPILHPNV GGIALVPLCP HALTARPVTL PDTSHIEIVL 250 260 270 280 290 300 LPQHDARIHF DGQARFDARA GDRLRVTRSP DVVRLLHPQG YSYFAMLREK LHWSATPRRP

References

[1]	"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1." Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R. Arch. Microbiol. 183:27-36(2005) [PubMed: 15551059] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR555306 Genomic DNA. Translation: CAI08845.1.
RefSeq	YP_159746.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5P1G9.
Genome annotation databases
GeneID	3179589.
GenomeReviews	Gene locus AZOSEA27200 in contig CR555306_GR.
KEGG	eba:ebA4805.
NMPDR	fig|76114.4.peg.2617.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5P1G9.
OMA	MEQFRNI.
Enzyme and pathway databases
BioCyc	ASP76114:EBA4805-MON.
Family and domain databases
HAMAP	MF_00361. [Tree]
InterPro	IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK_AZOSE

Accession

Primary (citable) accession number: Q5P1G9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	January 4, 2005
Last modified:	November 3, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)