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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotationSAAS annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotationImported
ORF Names:ebA5078Imported
OrganismiAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))Imported
Taxonomic identifieri76114 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum
Proteomesi
  • UP000006552 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi76114.ebA5078.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 114tRNA_anti_2InterPro annotationAdd BLAST93
Domaini138 – 451Exonuc_VII_LInterPro annotationAdd BLAST314

Sequence similaritiesi

Belongs to the XseA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229265.
KOiK03601.
OMAiNARRRWP.
OrthoDBiPOG091H02EK.

Family and domain databases

CDDicd04489. ExoVII_LU_OBF. 1 hit.
HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiView protein in InterPro
IPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
PANTHERiPTHR30008:SF1. PTHR30008:SF1. 1 hit.
PfamiView protein in Pfam
PF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5P112-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTELPHGDG DPCRLPSAGH VLSVAELNRL ARQTLESRFP LLWVGGELSN
60 70 80 90 100
LTRAPSGHLY FTLKDAQAQV RCTMWRNRAQ LLPFRPENGM RVEARALVTL
110 120 130 140 150
YEVRGDFQLG IEALRQAGVG NLFETFVRLK DRLAGEGLFD AALKRALPRY
160 170 180 190 200
PRRLGVVTSP AAAAWHDVLA TLRRRAPHLE VVLYPAPVQG EAARTRLAEA
210 220 230 240 250
VRVASARAAT DGIDLLLLVR GGGGIEDLWA FNDENLARAI RACPVPVVSG
260 270 280 290 300
IGHETDFTIA DFAADLRAAT PTGAAELASA GYHEACARLT SLGRTLSAAL
310 320 330 340 350
HYRLDTLAQR LDRAALRLVH PRERLAVAHE RTARLGVRLA AAMSRRLERL
360 370 380 390 400
HARNEQLCLR LEARRPDIDR EAERCARLAN RLVLAADRLI DRQSARLEGL
410 420 430 440 450
AAHLQHLAPH AVLARGYSIT RDAQGHILRT SAGVGSGEKV SVELATGRLH

ATVNSTDA
Length:458
Mass (Da):50,065
Last modified:January 4, 2005 - v1
Checksum:i3EEA1138040AEAA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR555306 Genomic DNA. Translation: CAI09002.1.

Genome annotation databases

EnsemblBacteriaiCAI09002; CAI09002; ebA5078.
KEGGieba:ebA5078.

Similar proteinsi

Entry informationi

Entry nameiQ5P112_AROAE
AccessioniPrimary (citable) accession number: Q5P112
Entry historyiIntegrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: September 27, 2017
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported