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Q5P112

- Q5P112_AROAE

UniProt

Q5P112 - Q5P112_AROAE

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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotationSAAS annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation
Exonucleolytic cleavage in either 5'- to 3'-or 3'- to 5'-direction to yield nucleoside 5'-phosphates.SAAS annotation

GO - Molecular functioni

  1. exodeoxyribonuclease VII activity Source: UniProtKB-HAMAP
  2. nucleic acid binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

ExonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciAARO76114:GJTA-2918-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotationImported
ORF Names:ebA5078Imported
OrganismiAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))Imported
Taxonomic identifieri76114 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum
ProteomesiUP000006552: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. exodeoxyribonuclease VII complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi76114.ebA5078.

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1570.
HOGENOMiHOG000229265.
KOiK03601.
OMAiHGSGHAY.
OrthoDBiEOG64R65J.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5P112-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQTELPHGDG DPCRLPSAGH VLSVAELNRL ARQTLESRFP LLWVGGELSN
60 70 80 90 100
LTRAPSGHLY FTLKDAQAQV RCTMWRNRAQ LLPFRPENGM RVEARALVTL
110 120 130 140 150
YEVRGDFQLG IEALRQAGVG NLFETFVRLK DRLAGEGLFD AALKRALPRY
160 170 180 190 200
PRRLGVVTSP AAAAWHDVLA TLRRRAPHLE VVLYPAPVQG EAARTRLAEA
210 220 230 240 250
VRVASARAAT DGIDLLLLVR GGGGIEDLWA FNDENLARAI RACPVPVVSG
260 270 280 290 300
IGHETDFTIA DFAADLRAAT PTGAAELASA GYHEACARLT SLGRTLSAAL
310 320 330 340 350
HYRLDTLAQR LDRAALRLVH PRERLAVAHE RTARLGVRLA AAMSRRLERL
360 370 380 390 400
HARNEQLCLR LEARRPDIDR EAERCARLAN RLVLAADRLI DRQSARLEGL
410 420 430 440 450
AAHLQHLAPH AVLARGYSIT RDAQGHILRT SAGVGSGEKV SVELATGRLH

ATVNSTDA
Length:458
Mass (Da):50,065
Last modified:January 4, 2005 - v1
Checksum:i3EEA1138040AEAA2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR555306 Genomic DNA. Translation: CAI09002.1.
RefSeqiYP_159903.1. NC_006513.1.

Genome annotation databases

EnsemblBacteriaiCAI09002; CAI09002; ebA5078.
GeneIDi3181698.
KEGGieba:ebA5078.
PATRICi20971960. VBIAroAro98752_2908.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR555306 Genomic DNA. Translation: CAI09002.1 .
RefSeqi YP_159903.1. NC_006513.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 76114.ebA5078.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI09002 ; CAI09002 ; ebA5078 .
GeneIDi 3181698.
KEGGi eba:ebA5078.
PATRICi 20971960. VBIAroAro98752_2908.

Phylogenomic databases

eggNOGi COG1570.
HOGENOMi HOG000229265.
KOi K03601.
OMAi HGSGHAY.
OrthoDBi EOG64R65J.

Enzyme and pathway databases

BioCyci AARO76114:GJTA-2918-MONOMER.

Family and domain databases

HAMAPi MF_00378. Exonuc_7_L.
InterProi IPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view ]
Pfami PF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00237. xseA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1."
    Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.
    Arch. Microbiol. 183:27-36(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: EbN1Imported.

Entry informationi

Entry nameiQ5P112_AROAE
AccessioniPrimary (citable) accession number: Q5P112
Entry historyi
Integrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: October 29, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3