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Q5P112

- Q5P112_AROAE

UniProt

Q5P112 - Q5P112_AROAE

Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (04 Jan 2005)
      Previous versions | rss
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    Functioni

    Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotationSAAS annotation

    Catalytic activityi

    Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation
    Exonucleolytic cleavage in either 5'- to 3'-or 3'- to 5'-direction to yield nucleoside 5'-phosphates.SAAS annotation

    GO - Molecular functioni

    1. exodeoxyribonuclease VII activity Source: UniProtKB-HAMAP
    2. nucleic acid binding Source: InterPro

    Keywords - Molecular functioni

    ExonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease

    Enzyme and pathway databases

    BioCyciAARO76114:GJTA-2918-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
    Alternative name(s):
    Exodeoxyribonuclease VII large subunitUniRule annotation
    Gene namesi
    Name:xseAUniRule annotationImported
    ORF Names:ebA5078Imported
    OrganismiAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))Imported
    Taxonomic identifieri76114 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum
    ProteomesiUP000006552: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. exodeoxyribonuclease VII complex Source: InterPro

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Heterooligomer composed of large and small subunits.UniRule annotationSAAS annotation

    Protein-protein interaction databases

    STRINGi76114.ebA5078.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the XseA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1570.
    HOGENOMiHOG000229265.
    KOiK03601.
    OMAiHGSGHAY.
    OrthoDBiEOG64R65J.

    Family and domain databases

    HAMAPiMF_00378. Exonuc_7_L.
    InterProiIPR003753. Exonuc_VII_L.
    IPR020579. Exonuc_VII_lsu_C.
    IPR025824. OB-fold_nuc-bd_dom.
    [Graphical view]
    PfamiPF02601. Exonuc_VII_L. 1 hit.
    PF13742. tRNA_anti_2. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00237. xseA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5P112-1 [UniParc]FASTAAdd to Basket

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    MQTELPHGDG DPCRLPSAGH VLSVAELNRL ARQTLESRFP LLWVGGELSN    50
    LTRAPSGHLY FTLKDAQAQV RCTMWRNRAQ LLPFRPENGM RVEARALVTL 100
    YEVRGDFQLG IEALRQAGVG NLFETFVRLK DRLAGEGLFD AALKRALPRY 150
    PRRLGVVTSP AAAAWHDVLA TLRRRAPHLE VVLYPAPVQG EAARTRLAEA 200
    VRVASARAAT DGIDLLLLVR GGGGIEDLWA FNDENLARAI RACPVPVVSG 250
    IGHETDFTIA DFAADLRAAT PTGAAELASA GYHEACARLT SLGRTLSAAL 300
    HYRLDTLAQR LDRAALRLVH PRERLAVAHE RTARLGVRLA AAMSRRLERL 350
    HARNEQLCLR LEARRPDIDR EAERCARLAN RLVLAADRLI DRQSARLEGL 400
    AAHLQHLAPH AVLARGYSIT RDAQGHILRT SAGVGSGEKV SVELATGRLH 450
    ATVNSTDA 458
    Length:458
    Mass (Da):50,065
    Last modified:January 4, 2005 - v1
    Checksum:i3EEA1138040AEAA2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR555306 Genomic DNA. Translation: CAI09002.1.
    RefSeqiYP_159903.1. NC_006513.1.

    Genome annotation databases

    EnsemblBacteriaiCAI09002; CAI09002; ebA5078.
    GeneIDi3181698.
    KEGGieba:ebA5078.
    PATRICi20971960. VBIAroAro98752_2908.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR555306 Genomic DNA. Translation: CAI09002.1 .
    RefSeqi YP_159903.1. NC_006513.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 76114.ebA5078.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAI09002 ; CAI09002 ; ebA5078 .
    GeneIDi 3181698.
    KEGGi eba:ebA5078.
    PATRICi 20971960. VBIAroAro98752_2908.

    Phylogenomic databases

    eggNOGi COG1570.
    HOGENOMi HOG000229265.
    KOi K03601.
    OMAi HGSGHAY.
    OrthoDBi EOG64R65J.

    Enzyme and pathway databases

    BioCyci AARO76114:GJTA-2918-MONOMER.

    Family and domain databases

    HAMAPi MF_00378. Exonuc_7_L.
    InterProi IPR003753. Exonuc_VII_L.
    IPR020579. Exonuc_VII_lsu_C.
    IPR025824. OB-fold_nuc-bd_dom.
    [Graphical view ]
    Pfami PF02601. Exonuc_VII_L. 1 hit.
    PF13742. tRNA_anti_2. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00237. xseA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1."
      Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.
      Arch. Microbiol. 183:27-36(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: EbN1Imported.

    Entry informationi

    Entry nameiQ5P112_AROAE
    AccessioniPrimary (citable) accession number: Q5P112
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 4, 2005
    Last sequence update: January 4, 2005
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3