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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotationSAAS annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ExonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciAARO76114:GJTA-2918-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotationSAAS annotation (EC:3.1.11.6UniRule annotationSAAS annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotationImported
ORF Names:ebA5078Imported
OrganismiAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))Imported
Taxonomic identifieri76114 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum
ProteomesiUP000006552 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi76114.ebA5078.

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1570.
HOGENOMiHOG000229265.
KOiK03601.
OMAiHGSGHAY.
OrthoDBiEOG64R65J.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5P112-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTELPHGDG DPCRLPSAGH VLSVAELNRL ARQTLESRFP LLWVGGELSN
60 70 80 90 100
LTRAPSGHLY FTLKDAQAQV RCTMWRNRAQ LLPFRPENGM RVEARALVTL
110 120 130 140 150
YEVRGDFQLG IEALRQAGVG NLFETFVRLK DRLAGEGLFD AALKRALPRY
160 170 180 190 200
PRRLGVVTSP AAAAWHDVLA TLRRRAPHLE VVLYPAPVQG EAARTRLAEA
210 220 230 240 250
VRVASARAAT DGIDLLLLVR GGGGIEDLWA FNDENLARAI RACPVPVVSG
260 270 280 290 300
IGHETDFTIA DFAADLRAAT PTGAAELASA GYHEACARLT SLGRTLSAAL
310 320 330 340 350
HYRLDTLAQR LDRAALRLVH PRERLAVAHE RTARLGVRLA AAMSRRLERL
360 370 380 390 400
HARNEQLCLR LEARRPDIDR EAERCARLAN RLVLAADRLI DRQSARLEGL
410 420 430 440 450
AAHLQHLAPH AVLARGYSIT RDAQGHILRT SAGVGSGEKV SVELATGRLH

ATVNSTDA
Length:458
Mass (Da):50,065
Last modified:January 4, 2005 - v1
Checksum:i3EEA1138040AEAA2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR555306 Genomic DNA. Translation: CAI09002.1.

Genome annotation databases

EnsemblBacteriaiCAI09002; CAI09002; ebA5078.
KEGGieba:ebA5078.
PATRICi20971960. VBIAroAro98752_2908.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR555306 Genomic DNA. Translation: CAI09002.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi76114.ebA5078.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAI09002; CAI09002; ebA5078.
KEGGieba:ebA5078.
PATRICi20971960. VBIAroAro98752_2908.

Phylogenomic databases

eggNOGiCOG1570.
HOGENOMiHOG000229265.
KOiK03601.
OMAiHGSGHAY.
OrthoDBiEOG64R65J.

Enzyme and pathway databases

BioCyciAARO76114:GJTA-2918-MONOMER.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1."
    Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.
    Arch. Microbiol. 183:27-36(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: EbN1Imported.

Entry informationi

Entry nameiQ5P112_AROAE
AccessioniPrimary (citable) accession number: Q5P112
Entry historyi
Integrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: July 22, 2015
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.