Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5NZG2

- LPXB_AROAE

UniProt

Q5NZG2 - LPXB_AROAE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciAARO76114:GJTA-3479-MONOMER.
UniPathwayiUPA00359; UER00481.

Protein family/group databases

CAZyiGT19. Glycosyltransferase Family 19.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
Gene namesi
Name:lpxBUniRule annotation
Ordered Locus Names:AZOSEA34270
ORF Names:ebA6002
OrganismiAromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1))
Taxonomic identifieri76114 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeAromatoleum
ProteomesiUP000006552: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 391391Lipid-A-disaccharide synthasePRO_0000255160Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi76114.ebA6002.

Structurei

3D structure databases

ProteinModelPortaliQ5NZG2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0763.
HOGENOMiHOG000018003.
KOiK00748.
OMAiIARMLVN.
OrthoDBiEOG6FBWZR.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5NZG2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATRIAMVAG EASGDLLASH LIRAIRQQVP EAEFYGIGGP KMQAEGFDAL
60 70 80 90 100
WPCERLAVHG YVDALKRYRE LSGIRKALLR RVQADRPDAF IGVDAPDFNL
110 120 130 140 150
WLEGRIRSSG IPAIHFVSPS IWAWRGGRIK GIARSVSHML CLFPFEPALY
160 170 180 190 200
EKAGIPVSYV GHPLADVFPL VPDRAAAREL LSLPTDCRIV ALLPGSRQSE
210 220 230 240 250
VRSLAATYIE TARLLAERHP DIGFVVPLAT RETRALFEQA LHAADADELP
260 270 280 290 300
IRLLFGHAVE AMTAADVVLV ASGTASLEAA LLKRPMVISY RIGKWQYRLM
310 320 330 340 350
KRMAYLPWVG LPNILCNDSV VPELLQDDAT PQALADALDR WLNDADACAE
360 370 380 390
LALRFDALHR ELRQDTAGRA AAAILPYLNR SPEWKPSRQS A
Length:391
Mass (Da):43,120
Last modified:January 4, 2005 - v1
Checksum:iA6607CA2A0110B54
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR555306 Genomic DNA. Translation: CAI09552.1.
RefSeqiYP_160453.1. NC_006513.1.

Genome annotation databases

EnsemblBacteriaiCAI09552; CAI09552; ebA6002.
GeneIDi3181086.
KEGGieba:ebA6002.
PATRICi20973075. VBIAroAro98752_3455.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR555306 Genomic DNA. Translation: CAI09552.1 .
RefSeqi YP_160453.1. NC_006513.1.

3D structure databases

ProteinModelPortali Q5NZG2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 76114.ebA6002.

Protein family/group databases

CAZyi GT19. Glycosyltransferase Family 19.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI09552 ; CAI09552 ; ebA6002 .
GeneIDi 3181086.
KEGGi eba:ebA6002.
PATRICi 20973075. VBIAroAro98752_3455.

Phylogenomic databases

eggNOGi COG0763.
HOGENOMi HOG000018003.
KOi K00748.
OMAi IARMLVN.
OrthoDBi EOG6FBWZR.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci AARO76114:GJTA-3479-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1."
    Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.
    Arch. Microbiol. 183:27-36(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: EbN1.

Entry informationi

Entry nameiLPXB_AROAE
AccessioniPrimary (citable) accession number: Q5NZG2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: January 4, 2005
Last modified: October 1, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3