Reviewed, UniProtKB/Swiss-Prot Q5NXP3 (PSD_AZOSE)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	AZOSEA40460
ORF Names:	ebA7135

Organism

Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) [Complete proteome] [HAMAP]

Taxonomic identifier

76114 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Aromatoleum

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664
Cofactor	Pyruvoyl group By similarity. HAMAP MF_00664
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphatidylethanolamine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cofactor binding Inferred from electronic annotation. Source: InterPro phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 183	183	Phosphatidylserine decarboxylase beta chain By similarity		PRO_0000262183
	Chain	184 – 215	32	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_0000262184
Sites
	Site	183 – 184	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	184	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5NXP3-1 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: 9ADC7D65420E37C5	FASTA	215	23,644
	10 20 30 40 50 60 MSNNYPHPLL AREGWPFIAI ALAVALVING AAGFGWALPF WLLFIFVVQF FRDPPRPIPQ 70 80 90 100 110 120 GAKDVLSPAD GRIVAIEPVR DPYLDRDSVK ISVFMNVFNV HSNRSPVDGE VVARWYNAGR 130 140 150 160 170 180 FVNAALDKAS VENERNALHL RTRDGHDVTC VQVAGLIARR ILCYVEAGAS LARGQRYGFI 190 200 210 RFGSRVDVYL PAGSRARVTI GDKVSASSTI LAELP

References

[1]	"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1." Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R. Arch. Microbiol. 183:27-36(2005) [PubMed: 15551059] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR555306 Genomic DNA. Translation: CAI10171.1.
RefSeq	YP_161072.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5NXP3.
Genome annotation databases
GeneID	3180683.
GenomeReviews	Gene locus AZOSEA40460 in contig CR555306_GR.
KEGG	eba:ebA7135.
NMPDR	fig|76114.4.peg.4062.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0688.
HOGENOM	HBG541103.
OMA	IFMSVFN.
Enzyme and pathway databases
BioCyc	ASP76114:EBA7135-MONOMER.
Family and domain databases
HAMAP	MF_00664. PS_decarb_type3. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR004428. PtdSer_deCO2ase_related. [Graphical view]
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00164. PS_decarb_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_AZOSE

Accession

Primary (citable) accession number: Q5NXP3

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	January 4, 2005
Last modified:	February 9, 2010
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)