ID   Q5NV67_HUMAN            Unreviewed;        99 AA.
AC   Q5NV67;
DT   04-JAN-2005, integrated into UniProtKB/TrEMBL.
DT   04-JAN-2005, sequence version 1.
DT   22-FEB-2023, entry version 91.
DE   SubName: Full=V1-11 protein {ECO:0000313|EMBL:BAA20897.1};
DE   Flags: Fragment;
GN   Name=V1-11 {ECO:0000313|EMBL:BAA20897.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAA20897.1};
RN   [1] {ECO:0000313|EMBL:BAA20897.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=9074928;
RA   Kawasaki K., Minoshima S., Mine E., Shibuya K., Shintani A., Schmeits J.L.,
RA   Wang J., Shimizu N.;
RT   "One-megabase sequence analysis of the human immunoglobulin lambda gene
RT   locus.";
RL   Genome Res. 7:250-261(1997).
RN   [2] {ECO:0007829|PDB:4Y5X}
RP   X-RAY CRYSTALLOGRAPHY (3.15 ANGSTROMS) OF 1-97, AND DISULFIDE BONDS.
RX   PubMed=25728669; DOI=10.1016/j.cell.2015.02.011;
RA   Moraga I., Wernig G., Wilmes S., Gryshkova V., Richter C.P., Hong W.J.,
RA   Sinha R., Guo F., Fabionar H., Wehrman T.S., Krutzik P., Demharter S.,
RA   Plo I., Weissman I.L., Minary P., Majeti R., Constantinescu S.N.,
RA   Piehler J., Garcia K.C.;
RT   "Tuning cytokine receptor signaling by re-orienting dimer geometry with
RT   surrogate ligands.";
RL   Cell 160:1196-1208(2015).
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DR   EMBL; D87010; BAA20897.1; -; Genomic_DNA.
DR   PDB; 4Y5X; X-ray; 3.15 A; B/E/H/K=1-97.
DR   AlphaFoldDB; Q5NV67; -.
DR   SMR; Q5NV67; -.
DR   PeptideAtlas; Q5NV67; -.
DR   Reactome; R-HSA-166663; Initial triggering of complement.
DR   Reactome; R-HSA-173623; Classical antibody-mediated complement activation.
DR   Reactome; R-HSA-198933; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
DR   Reactome; R-HSA-202733; Cell surface interactions at the vascular wall.
DR   Reactome; R-HSA-2029481; FCGR activation.
DR   Reactome; R-HSA-2029482; Regulation of actin dynamics for phagocytic cup formation.
DR   Reactome; R-HSA-2029485; Role of phospholipids in phagocytosis.
DR   Reactome; R-HSA-2168880; Scavenging of heme from plasma.
DR   Reactome; R-HSA-2454202; Fc epsilon receptor (FCERI) signaling.
DR   Reactome; R-HSA-2730905; Role of LAT2/NTAL/LAB on calcium mobilization.
DR   Reactome; R-HSA-2871796; FCERI mediated MAPK activation.
DR   Reactome; R-HSA-2871809; FCERI mediated Ca+2 mobilization.
DR   Reactome; R-HSA-2871837; FCERI mediated NF-kB activation.
DR   Reactome; R-HSA-9664323; FCGR3A-mediated IL10 synthesis.
DR   Reactome; R-HSA-9664422; FCGR3A-mediated phagocytosis.
DR   Reactome; R-HSA-977606; Regulation of Complement cascade.
DR   ChiTaRS; IGLV1-36; human.
DR   GO; GO:0005576; C:extracellular region; TAS:Reactome.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   PANTHER; PTHR23267:SF347; IMMUNOGLOBULIN LAMBDA VARIABLE 1-36; 1.
DR   PANTHER; PTHR23267; IMMUNOGLOBULIN LIGHT CHAIN; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4Y5X}.
FT   DOMAIN          1..99
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        22..89
FT                   /evidence="ECO:0007829|PDB:4Y5X"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:BAA20897.1"
FT   NON_TER         99
FT                   /evidence="ECO:0000313|EMBL:BAA20897.1"
SQ   SEQUENCE   99 AA;  10487 MW;  B8874209F126C286 CRC64;
     QSVLTQPPSV SEAPRQRVTI SCSGSSSNIG NNAVNWYQQL PGKAPKLLIY YDDLLPSGVS
     DRFSGSKSGT SASLAISGLQ SEDEADYYCA AWDDSLNGP
//