Q5NM53 (Q5NM53_ZYMMO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA gyrase subunit B 1 HAMAP MF_01898
EC=5.99.1.3 HAMAP MF_01898

Gene names

Name:	gyrB1 HAMAP MF_01898
Ordered Locus Names:	ZMO1583

Organism

Zymomonas mobilis [Complete proteome] [HAMAP]

Taxonomic identifier

542 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Zymomonas

Protein attributes

Sequence length	812 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. RuleBase RU003363 HAMAP MF_01898
Catalytic activity	ATP-dependent breakage, passage and rejoining of double-stranded DNA. RuleBase RU003363 SAAS SAAS002288 HAMAP MF_01898
Subunit structure	Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898
Subcellular location	Cytoplasm By similarity HAMAP MF_01898.
Sequence similarities	Belongs to the type II topoisomerase family. HAMAP MF_01898 RuleBase RU000380 Contains 1 Toprim domain. SAAS SAAS002288 HAMAP MF_01898

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_01898
Ligand	ATP-binding SAAS SAAS002288 HAMAP MF_01898 RuleBase RU000380 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS002288 HAMAP MF_01898 RuleBase RU000380
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro DNA-dependent DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5NM53 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: DB95E09A5274FC62	FASTA	812	90,659
	10 20 30 40 50 60 MATSKQHDDY DAGSIKVLRG LDAVRKRPGM YIGDTDDGSG LHHMVFEVSD NAIDEALAGY 70 80 90 100 110 120 CDLVKIAIYD DGSVSVEDNG RGIPTGIHPE EGVSAAEVIM TQLHAGGKFD NNANSNAYKV 130 140 150 160 170 180 SGGLHGVGVS VVNALSDYLE LTVWRDGQEH RMRFEHGVAV EPLQVVGASD KRGTRVRFHP 190 200 210 220 230 240 SAETFKITEF NFEKLEHRYR ELAFLNSGVR LQLTDKRTDP EKTVELFYEG GIAAFVKWLD 250 260 270 280 290 300 RAKTALIPEP VAIHGDRDDV MIDVALEWND SYYEQVLCFT NNIPQRDGGT HLAAFRAALT 310 320 330 340 350 360 RTLNNYADKS GLLKKEKVQL TGDDMREGLT AIISVKLPDP KFSSQTKDKL VSSEVRQPLE 370 380 390 400 410 420 SLMADKMAEW LEENPAHAKV IIQKIIDAAA AREAAKRARE LTRRKGVMDI ASLPGKLADC 430 440 450 460 470 480 QERDPTKSEI FIVEGDSAGG SAKQGRNRHN QAILPLKGKI LNTERSRLDR MLSSKEVGTL 490 500 510 520 530 540 IQALGTGIRD EFNIAKLRYH KIVIMTDADV DGAHIRTLLL TFFYRHMPEI IENGHLYIAQ 550 560 570 580 590 600 PPLFKVAKNR SEVYLKDEAA LDNYLMDAGV ASMMLHTDNG DRSGNDLHQM VEHARRTRLL 610 620 630 640 650 660 MNYVPNRYYA PLIETAALAG AFQSDIADEK RQDILKQVAE ILTRSDSESD ARWSVEFIPE 670 680 690 700 710 720 GFLFRRLWRG VTDAHTLDWN FIQSSEAAKL HQLAQEQAES YISTHPARLV TLAAQMDEEA 730 740 750 760 770 780 GQDIYRPSQL FEAILAVGSK GLSISRYKGL GEMNPEQLWE TTLDPANRSM LKVEVEQADV 790 800 810 ADEIFSRLMG DVVEPRRDFI QQNALSVANL DV

References

[1]

"The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4." Seo J.-S., Chong H., Park H.S., Yoon K.-O., Jung C., Kim J.J., Hong J.H., Kim H., Kim J.-H., Kil J.-I., Park C.J., Oh H.-M., Lee J.-S., Jin S.-J., Um H.-W., Lee H.-J., Oh S.-J., Kim J.Y. , Kang H.L., Lee S.Y., Lee K.J., Kang H.S. Nat. Biotechnol. 23:63-68(2005) [PubMed: 15592456] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 31821 / ZM4 / CP4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008692 Genomic DNA. Translation: AAV90207.1.
RefSeq	YP_163318.1. NC_006526.2.
3D structure databases
ProteinModelPortal	Q5NM53.
SMR	Q5NM53. Positions 15-387.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3188013.
GenomeReviews	Gene locus ZMO1583 in contig AE008692_GR.
KEGG	zmo:ZMO1583.
NMPDR	fig|264203.3.peg.57.
PATRIC	32568428. VBIZymMob102260_1490.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304889.
OMA	DCSSRDP.
ProtClustDB	PRK14939.
Enzyme and pathway databases
BioCyc	ZMOB264203:ZMO1583-MONOMER.
Family and domain databases
HAMAP	MF_01898. GyrB. [Tree]
InterPro	IPR003594. ATPase-like_ATP-bd. IPR011557. GyrB. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KO	K02470.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01059. GyrB. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5NM53_ZYMMO

Accession

Primary (citable) accession number: Q5NM53

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)