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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei138GTPUniRule annotation1
Binding sitei142GTPUniRule annotation1
Binding sitei186GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 25GTPUniRule annotation5
Nucleotide bindingi107 – 109GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciFTUL177416:G1G1C-218-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:FTT_0188Imported
OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)Imported
Taxonomic identifieri177416 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
Proteomesi
  • UP000001174 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

IntActiQ5NI93, 9 interactors
STRINGi177416.FTT_0188

Structurei

3D structure databases

SMRiQ5NI93
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5NI93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDFNDSMVS NAIIKVVGVG GGGGNAVQHM CEEVSDVEFF ALNTDGQALS
60 70 80 90 100
KSKVQNILQI GTNLTKGLGA GANPEIGKRA ATEDRAKIEQ LLEGADMVFI
110 120 130 140 150
TAGMGGGTGT GGAPVVAEVA KEMGILTVAV VTKPFPFEGP RRMKAAEQGI
160 170 180 190 200
DELTKHVDSI ITVPNEKLLS VLGKGASLID AFNAANDVLG NAVKGVSELI
210 220 230 240 250
TKPGLINVDF ADVRAVMTNM GLAMMGMGEA SGENRAREAA EAAISSPLLE
260 270 280 290 300
DINLDGAKGV IVNITAGMDM SIGEFEEVGE VIRSFISDEA IVIAGTVIDP
310 320 330 340 350
DMSDSMKVTV VVTGIEKVAM KRGFGVEKTS SLQQSASSFS NKTSAPFLRK
360 370 380
ETEVVTGASN APKTDSDDVN KSDIPSFLRR R
Length:381
Mass (Da):39,745
Last modified:February 1, 2005 - v1
Checksum:i4814CF5010D41430
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ749949 Genomic DNA Translation: CAG44821.1
RefSeqiWP_003017491.1, NZ_CP010290.1
YP_169249.1, NC_006570.2

Genome annotation databases

EnsemblBacteriaiAJI69016; AJI69016; BZ14_687
CAG44821; CAG44821; FTT_0188
GeneIDi3191126
KEGGiftu:FTT_0188
PATRICifig|177416.18.peg.208

Similar proteinsi

Entry informationi

Entry nameiQ5NI93_FRATT
AccessioniPrimary (citable) accession number: Q5NI93
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: March 28, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health