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Protein
Submitted name:

FMN-dependent dehydrogenase family protein

Gene

lldD1

Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

FMNPROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei29SubstratePROSITE-ProRule annotation1
Binding sitei111FMNPROSITE-ProRule annotation1
Binding sitei132FMNPROSITE-ProRule annotation1
Binding sitei134SubstratePROSITE-ProRule annotation1
Binding sitei160FMNPROSITE-ProRule annotation1
Binding sitei169SubstratePROSITE-ProRule annotation1
Binding sitei256FMNPROSITE-ProRule annotation1
Active sitei280Proton acceptorUniRule annotation1
Binding sitei283SubstratePROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi311 – 335FMNPROSITE-ProRule annotationAdd BLAST25

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseImported
LigandFlavoprotein, FMNPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
FMN-dependent dehydrogenase family proteinImported
Submitted name:
L-lactate dehydrogenaseImported (EC:1.1.2.3Imported)
Gene namesi
Name:lldD1Imported
Ordered Locus Names:FTT_0303cImported
ORF Names:BZ14_560Imported
OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)Imported
Taxonomic identifieri177416 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
Proteomesi
  • UP000001174 Componenti: Chromosome
  • UP000031862 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi177416.FTT_0303c.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 380FMN_dhInterPro annotationAdd BLAST361

Sequence similaritiesi

Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105DMF. Bacteria.
COG1304. LUCA.
HOGENOMiHOG000217464.
KOiK00101.
OMAiSVEKPFW.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR012133. Alpha-hydoxy_acid_DH_FMN.
IPR000262. FMN-dep_DH.
IPR008259. FMN_hydac_DH_AS.
PfamiView protein in Pfam
PF01070. FMN_dh. 1 hit.
PIRSFiPIRSF000138. Al-hdrx_acd_dh. 1 hit.
PROSITEiView protein in PROSITE
PS00557. FMN_HYDROXY_ACID_DH_1. 1 hit.
PS51349. FMN_HYDROXY_ACID_DH_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5NHZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSNLTKITS LDDMRKVYHR RVPKMFVDYC EAGSWQQQTL KYNQQDFGNY
60 70 80 90 100
LFRQKVLTDI QNRSLKTKIL GQEYKMPLVF APIGLLGMQH ADGEIHAARA
110 120 130 140 150
AEKFGIPFTL STMSICSTEE VAKHTTKPFW FQLYMMKDRK FMANLIASAK
160 170 180 190 200
HAGCSALVLT ADLQMLGDRH ADIKNGLTVP PKPTLKNLIN LSTKVPWCLN
210 220 230 240 250
MLKTSNRTFG NIVNHAANKG GFASLGKWTN EQFDLSLNWH DVEWVQKQWN
260 270 280 290 300
GRMIIKGIMD TQDAIMAQNT GADAIVVSNH GGRQLDGAPS SISVLEEIID
310 320 330 340 350
AVDRKLEVLI DSGIRTGQDL LKAKALGATA GLIGRPMVYG LGAYGEQGAY
360 370 380
RVLEIFYQEM DKTMAFCGHT NINNVDKSIL IKRNT
Length:385
Mass (Da):43,064
Last modified:February 1, 2005 - v1
Checksum:iD78A4A3273758FCA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP010290 Genomic DNA. Translation: AJI68794.1.
AJ749949 Genomic DNA. Translation: CAG44936.1.
RefSeqiWP_003014268.1. NZ_CP010290.1.
YP_169352.1. NC_006570.2.

Genome annotation databases

EnsemblBacteriaiAJI68794; AJI68794; BZ14_560.
CAG44936; CAG44936; FTT_0303c.
GeneIDi3191464.
KEGGiftu:FTT_0303c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP010290 Genomic DNA. Translation: AJI68794.1.
AJ749949 Genomic DNA. Translation: CAG44936.1.
RefSeqiWP_003014268.1. NZ_CP010290.1.
YP_169352.1. NC_006570.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi177416.FTT_0303c.

Protocols and materials databases

DNASUi3191464.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAJI68794; AJI68794; BZ14_560.
CAG44936; CAG44936; FTT_0303c.
GeneIDi3191464.
KEGGiftu:FTT_0303c.

Phylogenomic databases

eggNOGiENOG4105DMF. Bacteria.
COG1304. LUCA.
HOGENOMiHOG000217464.
KOiK00101.
OMAiSVEKPFW.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR012133. Alpha-hydoxy_acid_DH_FMN.
IPR000262. FMN-dep_DH.
IPR008259. FMN_hydac_DH_AS.
PfamiView protein in Pfam
PF01070. FMN_dh. 1 hit.
PIRSFiPIRSF000138. Al-hdrx_acd_dh. 1 hit.
PROSITEiView protein in PROSITE
PS00557. FMN_HYDROXY_ACID_DH_1. 1 hit.
PS51349. FMN_HYDROXY_ACID_DH_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5NHZ0_FRATT
AccessioniPrimary (citable) accession number: Q5NHZ0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: February 15, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.