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Protein

Chaperone protein HtpG

Gene

htpG

Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Molecular chaperone. Has ATPase activity.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciFTUL177416:G1G1C-416-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein HtpGUniRule annotation
Alternative name(s):
Heat shock protein HtpGUniRule annotation
High temperature protein GUniRule annotation
Gene namesi
Name:htpGUniRule annotation
Ordered Locus Names:FTT_0356
OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Taxonomic identifieri177416 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
Proteomesi
  • UP000001174 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002242081 – 628Chaperone protein HtpGAdd BLAST628

Interactioni

Subunit structurei

Homodimer.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ5NHT8, 2 interactors
STRINGi177416.FTT_0356

Structurei

3D structure databases

ProteinModelPortaliQ5NHT8
SMRiQ5NHT8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 337A; substrate-bindingUniRule annotationAdd BLAST337
Regioni338 – 554BUniRule annotationAdd BLAST217
Regioni555 – 628CUniRule annotationAdd BLAST74

Sequence similaritiesi

Belongs to the heat shock protein 90 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJX Bacteria
COG0326 LUCA
HOGENOMiHOG000031989
KOiK04079
OMAiSDHEIFL

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di1.20.120.790, 1 hit
3.30.565.10, 1 hit
HAMAPiMF_00505 HSP90, 1 hit
InterProiView protein in InterPro
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR019805 Heat_shock_protein_90_CS
IPR037196 HSP90_C
IPR001404 Hsp90_fam
IPR020575 Hsp90_N
IPR020568 Ribosomal_S5_D2-typ_fold
PANTHERiPTHR11528 PTHR11528, 1 hit
PfamiView protein in Pfam
PF00183 HSP90, 1 hit
PIRSFiPIRSF002583 Hsp90, 1 hit
PRINTSiPR00775 HEATSHOCK90
SMARTiView protein in SMART
SM00387 HATPase_c, 1 hit
SUPFAMiSSF110942 SSF110942, 1 hit
SSF54211 SSF54211, 1 hit
SSF55874 SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS00298 HSP90, 1 hit

Sequencei

Sequence statusi: Complete.

Q5NHT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEKKYTFET EVDKLLHLVI HSLYSNREIF LRELVSNSSD AIEKLRYESI
60 70 80 90 100
SNAALNEDDT DYAIRIDFDK DAKTITVSDN GIGMTEEEVI ENLGTIAKSG
110 120 130 140 150
TKKFLESLTG DKSKDNELIG QFGVGFYSSF IVADKVTVRT RKAGQDKSQA
160 170 180 190 200
TKWVSDAQNG FTVETITKEK RGTEVILHIK KEHLDLLEYH VLKGLVNKYS
210 220 230 240 250
DCINTSIQMK KVEYDKDGKQ TVKDEYETVN NTKAIWLRSK DEVTDEEYQE
260 270 280 290 300
FYKYISHDFA DALMWIHNKV EGNLEYNSLL YIPQNKPFDF WNRDKDYGLS
310 320 330 340 350
LYVRRVFIME NKELLPPYLR FVKGVIDSAD LPLNVSREIL QHNKVIDKIK
360 370 380 390 400
KAITTKILSE LKKLASKDKE KYQKFWDSFG QVLKEGVSDD YSNKEKIAGL
410 420 430 440 450
LRFATTQSGD SKQTVSLADY ISRMKEGQDT IYYITSDSYK AAANNPQLEA
460 470 480 490 500
FKKKGIEVIL MTDRIDEWMM STLTEFDGKH MKSIIKGDID LDRFETPENK
510 520 530 540 550
EKFEKEAKDF EKVLKEIKEV LKDKVEDVRL SKRLTDSPSC VVVNDYGMSL
560 570 580 590 600
HMQKMMEEAG QSFMPGMGMK PILELNAEHN LVQKLKNEAD TEIFADLSEL
610 620
LLLQAMFVEG AKIEDPMAFV KLVNKYIR
Length:628
Mass (Da):72,349
Last modified:February 1, 2005 - v1
Checksum:i2496B9EC4F230DAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ749949 Genomic DNA Translation: CAG44989.1
RefSeqiWP_003020060.1, NZ_CP010290.1
YP_169404.1, NC_006570.2

Genome annotation databases

EnsemblBacteriaiCAG44989; CAG44989; FTT_0356
GeneIDi3191490
KEGGiftu:FTT_0356

Similar proteinsi

Entry informationi

Entry nameiHTPG_FRATT
AccessioniPrimary (citable) accession number: Q5NHT8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: February 1, 2005
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health