Q5NHN2 (GLGA_FRATT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	FTT_0416

Organism

Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4) [Reference proteome] [HAMAP]

Taxonomic identifier

177416 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella › Francisella tularensis › Francisella tularensis subsp. tularensis

Protein attributes

Sequence length	489 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 489	489	Glycogen synthase HAMAP-Rule MF_00484		PRO_0000188615
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5NHN2 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: D94EF862CE9D169A	FASTA	489	53,536
	10 20 30 40 50 60 MRVLHVCSEL YPILKTGGLA DVTAALPPAL AGFGVDSRVL VPGFPAFINA IKDKQLLINI 70 80 90 100 110 120 PSRFGAEEIN IFLAKISNTK IDIYVIDAPS LFARPGNPYA DSSNQAYADN YLRFALLGWV 130 140 150 160 170 180 AARISEGLDA KWKPEIVHSH DWHAGLVPAY IKASELASGK KAVKTVFTVH NLAYQGLFPM 190 200 210 220 230 240 SVFAELDLPG IFLSMNGLEF YGQVSFMKAG LYFADKITTV SPTYAKEIQI YEQGCGLEGL 250 260 270 280 290 300 LADRHNDLYG VLNGVDPQIW NPKKDSLIAT NYSSTTVATG KAKCKLALQQ MMGLAEKEDA 310 320 330 340 350 360 LLFGIVTRLT EQKGLNLLIE AIGEITSRGG QIVLLGSGDK ALEEVFLAAA KKYSKSIAVQ 370 380 390 400 410 420 IGYDEEQAHR IIAGSDVIMV PSRFEPCGLT QLYGLTYGTL PLVHKVGGLA DTVIDSSLEN 430 440 450 460 470 480 LADGTATGFV FDEFSVESLT LAIRRAFALY NRKTDWKKVR KTAMQQQVTW DSSAEKIYQI YKNLVRENN

References

[1]

"The complete genome sequence of Francisella tularensis, the causative agent of tularemia." Larsson P., Oyston P.C.F., Chain P., Chu M.C., Duffield M., Fuxelius H.-H., Garcia E., Haelltorp G., Johansson D., Isherwood K.E., Karp P.D., Larsson E., Liu Y., Michell S., Prior J., Prior R., Malfatti S., Sjoestedt A. , Svensson K., Thompson N., Vergez L., Wagg J.K., Wren B.W., Lindler L.E., Andersson S.G.E., Forsman M., Titball R.W. Nat. Genet. 37:153-159(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SCHU S4 / Schu 4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ749949 Genomic DNA. Translation: CAG45049.1.
RefSeq	YP_169460.1. NC_006570.2.
3D structure databases
ProteinModelPortal	Q5NHN2.
ModBase	Search...
Protein-protein interaction databases
STRING	177416.FTT_0416.
Protocols and materials databases
DNASU	3192504.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAG45049; CAG45049; FTT_0416.
GeneID	3192504.
KEGG	ftu:FTT_0416.
Phylogenomic databases
eggNOG	COG0297.
HOGENOM	HOG000294941.
KO	K00703.
OMA	TKFAFLC.
ProtClustDB	PRK00654.
Enzyme and pathway databases
UniPathway	UPA00164.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth.
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_FRATT

Accession

Primary (citable) accession number: Q5NHN2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	February 1, 2005
Last modified:	May 1, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program