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Q5NGI4

- UBIA_FRATT

UniProt

Q5NGI4 - UBIA_FRATT

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Protein

4-hydroxybenzoate octaprenyltransferase

Gene
ubiA, FTT_0856c
Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Synthesis of 3-octaprenyl-4-hydroxybenzoate By similarity.UniRule annotation

Catalytic activityi

4-hydroxybenzoate + farnesylfarnesylgeraniol = 3-octaprenyl-4-hydroxybenzoate.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. prenyltransferase activity Source: InterPro

GO - Biological processi

  1. ubiquinone biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Ubiquinone biosynthesis

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciFTUL177416:GNBP-873-MONOMER.
UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
4-hydroxybenzoate octaprenyltransferase (EC:2.5.1.-)
Alternative name(s):
4-HB polyprenyltransferase
Gene namesi
Name:ubiA
Ordered Locus Names:FTT_0856c
OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Taxonomic identifieri177416 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
ProteomesiUP000001174: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei42 – 6221Helical; Reviewed predictionAdd
BLAST
Transmembranei85 – 10521Helical; Reviewed predictionAdd
BLAST
Transmembranei107 – 12721Helical; Reviewed predictionAdd
BLAST
Transmembranei134 – 15421Helical; Reviewed predictionAdd
BLAST
Transmembranei165 – 18521Helical; Reviewed predictionAdd
BLAST
Transmembranei211 – 23121Helical; Reviewed predictionAdd
BLAST
Transmembranei233 – 25321Helical; Reviewed predictionAdd
BLAST
Transmembranei261 – 28121Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2842844-hydroxybenzoate octaprenyltransferaseUniRule annotationPRO_0000262797Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi177416.FTT_0856c.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0382.
HOGENOMiHOG000003696.
KOiK03179.
OMAiGMPMAFT.
OrthoDBiEOG680X3B.

Family and domain databases

HAMAPiMF_01635. UbiA.
InterProiIPR006370. HB_polyprenyl-transferase.
IPR000537. UbiA_prenyltransferase.
[Graphical view]
PfamiPF01040. UbiA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01474. ubiA_proteo. 1 hit.
PROSITEiPS00943. UBIA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5NGI4-1 [UniParc]FASTAAdd to Basket

« Hide

MNKQQLKAYF MLMRLHRPIP ILLILWPTLT ALVLASHGLP DISYLVIFTI    50
GVVVMRTVGC IINDIADVDF DKHVARTNTR PLTSGQLSIK NAIWLCISLT 100
LVAFICVLFL NLYTILLSFV ALFLAILYPF CKRFFAIPQL ILGLAFNFGI 150
FMAFSTIQNQ IPVEAWIFYI ATICWTIAYD TIYALADREF DLEIGIKSSA 200
VLFGNKVFRY ILLFNFLSLL LLIILGIYCD FNSFFYLGVV ICSLFFVRNY 250
FLYKKLGITN CINAFSANHW IGLIIFIIAV IQYI 284
Length:284
Mass (Da):32,489
Last modified:February 1, 2005 - v1
Checksum:i31B73AF6BB804F15
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ749949 Genomic DNA. Translation: CAG45489.1.
RefSeqiYP_169858.1. NC_006570.2.

Genome annotation databases

EnsemblBacteriaiCAG45489; CAG45489; FTT_0856c.
GeneIDi3192470.
KEGGiftu:FTT_0856c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ749949 Genomic DNA. Translation: CAG45489.1 .
RefSeqi YP_169858.1. NC_006570.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 177416.FTT_0856c.

Protocols and materials databases

DNASUi 3192470.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAG45489 ; CAG45489 ; FTT_0856c .
GeneIDi 3192470.
KEGGi ftu:FTT_0856c.

Phylogenomic databases

eggNOGi COG0382.
HOGENOMi HOG000003696.
KOi K03179.
OMAi GMPMAFT.
OrthoDBi EOG680X3B.

Enzyme and pathway databases

UniPathwayi UPA00232 .
BioCyci FTUL177416:GNBP-873-MONOMER.

Family and domain databases

HAMAPi MF_01635. UbiA.
InterProi IPR006370. HB_polyprenyl-transferase.
IPR000537. UbiA_prenyltransferase.
[Graphical view ]
Pfami PF01040. UbiA. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01474. ubiA_proteo. 1 hit.
PROSITEi PS00943. UBIA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SCHU S4 / Schu 4.

Entry informationi

Entry nameiUBIA_FRATT
AccessioniPrimary (citable) accession number: Q5NGI4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: February 1, 2005
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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