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Q5NGI4

- UBIA_FRATT

UniProt

Q5NGI4 - UBIA_FRATT

Protein

4-hydroxybenzoate octaprenyltransferase

Gene

ubiA

Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (01 Feb 2005)
      Previous versions | rss
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    Functioni

    Synthesis of 3-octaprenyl-4-hydroxybenzoate.UniRule annotation

    Catalytic activityi

    4-hydroxybenzoate + farnesylfarnesylgeraniol = 3-octaprenyl-4-hydroxybenzoate.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. prenyltransferase activity Source: InterPro

    GO - Biological processi

    1. ubiquinone biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Ubiquinone biosynthesis

    Keywords - Ligandi

    Magnesium

    Enzyme and pathway databases

    BioCyciFTUL177416:GNBP-873-MONOMER.
    UniPathwayiUPA00232.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    4-hydroxybenzoate octaprenyltransferaseUniRule annotation (EC:2.5.1.-UniRule annotation)
    Alternative name(s):
    4-HB polyprenyltransferaseUniRule annotation
    Gene namesi
    Name:ubiAUniRule annotation
    Ordered Locus Names:FTT_0856c
    OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
    Taxonomic identifieri177416 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
    ProteomesiUP000001174: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2842844-hydroxybenzoate octaprenyltransferasePRO_0000262797Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi177416.FTT_0856c.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei42 – 6221HelicalUniRule annotationAdd
    BLAST
    Transmembranei85 – 10521HelicalUniRule annotationAdd
    BLAST
    Transmembranei107 – 12721HelicalUniRule annotationAdd
    BLAST
    Transmembranei134 – 15421HelicalUniRule annotationAdd
    BLAST
    Transmembranei165 – 18521HelicalUniRule annotationAdd
    BLAST
    Transmembranei211 – 23121HelicalUniRule annotationAdd
    BLAST
    Transmembranei233 – 25321HelicalUniRule annotationAdd
    BLAST
    Transmembranei261 – 28121HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UbiA prenyltransferase family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0382.
    HOGENOMiHOG000003696.
    KOiK03179.
    OMAiGMPMAFT.
    OrthoDBiEOG680X3B.

    Family and domain databases

    HAMAPiMF_01635. UbiA.
    InterProiIPR006370. HB_polyprenyl-transferase.
    IPR000537. UbiA_prenyltransferase.
    [Graphical view]
    PfamiPF01040. UbiA. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01474. ubiA_proteo. 1 hit.
    PROSITEiPS00943. UBIA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5NGI4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKQQLKAYF MLMRLHRPIP ILLILWPTLT ALVLASHGLP DISYLVIFTI    50
    GVVVMRTVGC IINDIADVDF DKHVARTNTR PLTSGQLSIK NAIWLCISLT 100
    LVAFICVLFL NLYTILLSFV ALFLAILYPF CKRFFAIPQL ILGLAFNFGI 150
    FMAFSTIQNQ IPVEAWIFYI ATICWTIAYD TIYALADREF DLEIGIKSSA 200
    VLFGNKVFRY ILLFNFLSLL LLIILGIYCD FNSFFYLGVV ICSLFFVRNY 250
    FLYKKLGITN CINAFSANHW IGLIIFIIAV IQYI 284
    Length:284
    Mass (Da):32,489
    Last modified:February 1, 2005 - v1
    Checksum:i31B73AF6BB804F15
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ749949 Genomic DNA. Translation: CAG45489.1.
    RefSeqiYP_169858.1. NC_006570.2.

    Genome annotation databases

    EnsemblBacteriaiCAG45489; CAG45489; FTT_0856c.
    GeneIDi3192470.
    KEGGiftu:FTT_0856c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ749949 Genomic DNA. Translation: CAG45489.1 .
    RefSeqi YP_169858.1. NC_006570.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 177416.FTT_0856c.

    Protocols and materials databases

    DNASUi 3192470.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAG45489 ; CAG45489 ; FTT_0856c .
    GeneIDi 3192470.
    KEGGi ftu:FTT_0856c.

    Phylogenomic databases

    eggNOGi COG0382.
    HOGENOMi HOG000003696.
    KOi K03179.
    OMAi GMPMAFT.
    OrthoDBi EOG680X3B.

    Enzyme and pathway databases

    UniPathwayi UPA00232 .
    BioCyci FTUL177416:GNBP-873-MONOMER.

    Family and domain databases

    HAMAPi MF_01635. UbiA.
    InterProi IPR006370. HB_polyprenyl-transferase.
    IPR000537. UbiA_prenyltransferase.
    [Graphical view ]
    Pfami PF01040. UbiA. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01474. ubiA_proteo. 1 hit.
    PROSITEi PS00943. UBIA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SCHU S4 / Schu 4.

    Entry informationi

    Entry nameiUBIA_FRATT
    AccessioniPrimary (citable) accession number: Q5NGI4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 28, 2006
    Last sequence update: February 1, 2005
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3