Q5NGB3 (Q5NGB3_FRATT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
8-amino-7-oxononanoate synthase EMBL CAG45569.1
EC=2.3.1.47 EMBL CAG45569.1

Gene names

Name:	bioF EMBL CAG45569.1
Ordered Locus Names:	FTT_0936c

Organism

Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4) [Reference proteome] [HAMAP] EMBL CAG45569.1

Taxonomic identifier

177416 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella › Francisella tularensis › Francisella tularensis subsp. tularensis

Protein attributes

Sequence length	375 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Acyltransferase EMBL CAG45569.1 Transferase
Technical term	3D-structure PDB 4IW7 Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	8-amino-7-oxononanoate synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	330	1	Cysteine sulfinic acid (-SO2H) PDB 4IW7

Sequences

	Sequence		Length	Mass (Da)
	Q5NGB3 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: 886A7F5240C118B5	FASTA	375	42,568
	10 20 30 40 50 60 MLNLQDKYTQ YQRDNLLREL TPFIKDDSII DFTTSDYLNL SSAHNLKHAI VNGFDKYGFG 70 80 90 100 110 120 SKGSNIVCGY TDETQQFEHE FAKFINYPRA IFFSSGFMAN LAIYSTLFSK HDSIFADKYI 130 140 150 160 170 180 HASIIDGIKL SQAKLRRYKH QQLSQLQDIY DGKSFITTEG VFSTSGSITQ LDKLAKITPE 190 200 210 220 230 240 KLIVDEAHSF GVLGKNGRGA INSFRISYKN CLICVFPLGK AFGGVGAVVC TTEAIAEYLI 250 260 270 280 290 300 QFARNYIYTT ALPPMILKAA LIQLKNLENA NDNRARLQQN ITFFNELCDA KDLELVSKDL 310 320 330 340 350 360 SPIRSIQLNN ANLAIRLKDK LFENKIIVSC FRYPTVPKDQ AILRFSLHSN NTFDQIQQAL 370 EIISKEVKYE YIRSN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome sequence of Francisella tularensis, the causative agent of tularemia." Larsson P., Oyston P.C.F., Chain P., Chu M.C., Duffield M., Fuxelius H.-H., Garcia E., Haelltorp G., Johansson D., Isherwood K.E., Karp P.D., Larsson E., Liu Y., Michell S., Prior J., Prior R., Malfatti S., Sjoestedt A. , Svensson K., Thompson N., Vergez L., Wagg J.K., Wren B.W., Lindler L.E., Andersson S.G.E., Forsman M., Titball R.W. Nat. Genet. 37:153-159(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SCHU S4 / Schu 4.
[2]	"Crystal structure of 8-amino-7-oxononanoate synthase (bioF) from Francisella tularensis." Newcomb W., Niedzialkowska E., Porebski P.J., Grimshaw S., Anderson W.F., Minor W. Submitted (JAN-2013) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS), SULFINATION AT CYS-330.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AJ749949 Genomic DNA. Translation: CAG45569.1.

RefSeq

YP_169929.1. NC_006570.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4IW7	X-ray	2.25	A	1-375	[»]

ProteinModelPortal

Q5NGB3.

ModBase

Search...

Protein-protein interaction databases

STRING

177416.FTT_0936c.

Protocols and materials databases

DNASU

3190975.

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

CAG45569; CAG45569; FTT_0936c.

GeneID

3190975.

KEGG

ftu:FTT_0936c.

Phylogenomic databases

HOGENOM

HOG000221021.

KO

K00652.

OMA

GNHASIV.

ProtClustDB

CLSK934759.

Family and domain databases

Gene3D

3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.

InterPro

IPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]

Pfam

PF00155. Aminotran_1_2. 1 hit.
[Graphical view]

SUPFAM

SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q5NGB3_FRATT

Accession

Primary (citable) accession number: Q5NGB3

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)