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Q5NGB3

- Q5NGB3_FRATT

UniProt

Q5NGB3 - Q5NGB3_FRATT

Protein
Submitted name:

8-amino-7-oxononanoate synthase

Gene

bioF

Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (01 Feb 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 8-amino-7-oxononanoate synthase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseImported, Transferase

    Enzyme and pathway databases

    BioCyciFTUL177416:GNBP-954-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    8-amino-7-oxononanoate synthaseImported (EC:2.3.1.47Imported)
    Gene namesi
    Name:bioFImported
    Ordered Locus Names:FTT_0936cImported
    OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)Imported
    Taxonomic identifieri177416 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
    ProteomesiUP000001174: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei330 – 3301Cysteine sulfinic acid (-SO2H)Imported

    Interactioni

    Protein-protein interaction databases

    STRINGi177416.FTT_0936c.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4IW7X-ray2.25A1-375[»]
    ProteinModelPortaliQ5NGB3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000221021.
    KOiK00652.
    OMAiGEEATVM.
    OrthoDBiEOG6Q8HZD.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR004839. Aminotransferase_I/II.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PfamiPF00155. Aminotran_1_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5NGB3-1 [UniParc]FASTAAdd to Basket

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    MLNLQDKYTQ YQRDNLLREL TPFIKDDSII DFTTSDYLNL SSAHNLKHAI    50
    VNGFDKYGFG SKGSNIVCGY TDETQQFEHE FAKFINYPRA IFFSSGFMAN 100
    LAIYSTLFSK HDSIFADKYI HASIIDGIKL SQAKLRRYKH QQLSQLQDIY 150
    DGKSFITTEG VFSTSGSITQ LDKLAKITPE KLIVDEAHSF GVLGKNGRGA 200
    INSFRISYKN CLICVFPLGK AFGGVGAVVC TTEAIAEYLI QFARNYIYTT 250
    ALPPMILKAA LIQLKNLENA NDNRARLQQN ITFFNELCDA KDLELVSKDL 300
    SPIRSIQLNN ANLAIRLKDK LFENKIIVSC FRYPTVPKDQ AILRFSLHSN 350
    NTFDQIQQAL EIISKEVKYE YIRSN 375
    Length:375
    Mass (Da):42,568
    Last modified:February 1, 2005 - v1
    Checksum:i886A7F5240C118B5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ749949 Genomic DNA. Translation: CAG45569.1.
    RefSeqiYP_169929.1. NC_006570.2.

    Genome annotation databases

    EnsemblBacteriaiCAG45569; CAG45569; FTT_0936c.
    GeneIDi3190975.
    KEGGiftu:FTT_0936c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ749949 Genomic DNA. Translation: CAG45569.1 .
    RefSeqi YP_169929.1. NC_006570.2.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4IW7 X-ray 2.25 A 1-375 [» ]
    ProteinModelPortali Q5NGB3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 177416.FTT_0936c.

    Protocols and materials databases

    DNASUi 3190975.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAG45569 ; CAG45569 ; FTT_0936c .
    GeneIDi 3190975.
    KEGGi ftu:FTT_0936c.

    Phylogenomic databases

    HOGENOMi HOG000221021.
    KOi K00652.
    OMAi GEEATVM.
    OrthoDBi EOG6Q8HZD.

    Enzyme and pathway databases

    BioCyci FTUL177416:GNBP-954-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR004839. Aminotransferase_I/II.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    Pfami PF00155. Aminotran_1_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SCHU S4 / Schu 4Imported.
    2. "Crystal structure of 8-amino-7-oxononanoate synthase (bioF) from Francisella tularensis."
      Newcomb W., Niedzialkowska E., Porebski P.J., Grimshaw S., Anderson W.F., Minor W.
      Submitted (JAN-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS).

    Entry informationi

    Entry nameiQ5NGB3_FRATT
    AccessioniPrimary (citable) accession number: Q5NGB3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 1, 2005
    Last sequence update: February 1, 2005
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3