SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5NFC4

- G6PI_FRATT

UniProt

Q5NFC4 - G6PI_FRATT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glucose-6-phosphate isomerase
Gene
pgi, FTT_1315c
Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei346 – 3461Proton donor By similarity
Active sitei377 – 3771 By similarity
Active sitei505 – 5051 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciFTUL177416:GNBP-1340-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:FTT_1315c
OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Taxonomic identifieri177416 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
ProteomesiUP000001174: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 540540Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000180644Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiQ5NFC4. 2 interactions.
STRINGi177416.FTT_1315c.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 53
Helixi6 – 127
Helixi18 – 247
Helixi28 – 314
Beta strandi33 – 364
Beta strandi39 – 424
Helixi50 – 6213
Helixi65 – 7410
Turni80 – 834
Helixi88 – 925
Helixi106 – 12520
Beta strandi139 – 1435
Helixi146 – 1483
Helixi150 – 1589
Helixi160 – 1623
Beta strandi168 – 1725
Beta strandi174 – 1763
Helixi177 – 1848
Helixi189 – 1913
Beta strandi192 – 1976
Beta strandi199 – 2013
Helixi204 – 22118
Helixi224 – 2296
Beta strandi231 – 2344
Helixi238 – 2447
Helixi248 – 2503
Beta strandi251 – 2533
Helixi260 – 2623
Helixi267 – 2693
Helixi270 – 2767
Helixi278 – 29720
Helixi300 – 3023
Helixi304 – 31815
Beta strandi323 – 3286
Helixi331 – 3333
Helixi336 – 34813
Beta strandi366 – 3694
Helixi374 – 3774
Helixi380 – 3856
Beta strandi392 – 3998
Beta strandi401 – 4033
Helixi405 – 42420
Helixi428 – 43710
Helixi442 – 45211
Beta strandi460 – 4667
Helixi470 – 49122
Helixi499 – 5013
Helixi502 – 51615
Helixi521 – 5255
Helixi528 – 53811

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3LJKX-ray1.48A1-540[»]
3M5PX-ray1.65A1-540[»]
3Q7IX-ray1.54A1-540[»]
3Q88X-ray1.70A1-540[»]
ProteinModelPortaliQ5NFC4.

Miscellaneous databases

EvolutionaryTraceiQ5NFC4.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5NFC4-1 [UniParc]FASTAAdd to Basket

« Hide

MLFCDDSKKY LKEQNINLKN EFDKDDKRVE KFSLKHQNIY FDYSKNLIND    50
YILKSLLESA EKSSLKDKIK QMFNGAKINS TEHRAVLHTA LRDLSSTPLI 100
VDGQDIRQEV TKEKQRVKEL VEKVVSGRWR GFSGKKITDI VNIGIGGSDL 150
GPKMVVRALQ PYHCTDLKVH FVSNVDADSL LQALHVVDPE TTLFIIASKS 200
FSTEETLLNS ISAREWLLDH YEDEKAVANH FVAISSKLDK VKEFGIDLEH 250
CYKMWDWVGG RYSLWSSIGM SIAFAIGYDN FEKLLAGAYS VDKHFKETEF 300
SKNIPVIMAL LASYYSCTYN SQSQALLPYD ERLCYFVDYL QQADMESNGK 350
SVNIAGETVN YQTGVVLWGG VGTNGQHAFH QLLHQGNIFI PVDFIAIATS 400
HHNYDNHQQA LLANCFAQSQ ALMFGQSYDM VYNELLKSGL NETQAKELAA 450
HKVIPGNRPS TTILLDELSP YSLGALIALY EHKIFVQGVL WDINSYDQWG 500
VELGKKLGKN ILKAMNDDSS DEYQNLDDST RQLIAKVKNK 540
Length:540
Mass (Da):61,152
Last modified:February 1, 2005 - v1
Checksum:i4D34257EBD77D2FD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ749949 Genomic DNA. Translation: CAG45948.1.
RefSeqiYP_170268.1. NC_006570.2.

Genome annotation databases

EnsemblBacteriaiCAG45948; CAG45948; FTT_1315c.
GeneIDi3191335.
KEGGiftu:FTT_1315c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ749949 Genomic DNA. Translation: CAG45948.1 .
RefSeqi YP_170268.1. NC_006570.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3LJK X-ray 1.48 A 1-540 [» ]
3M5P X-ray 1.65 A 1-540 [» ]
3Q7I X-ray 1.54 A 1-540 [» ]
3Q88 X-ray 1.70 A 1-540 [» ]
ProteinModelPortali Q5NFC4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q5NFC4. 2 interactions.
STRINGi 177416.FTT_1315c.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAG45948 ; CAG45948 ; FTT_1315c .
GeneIDi 3191335.
KEGGi ftu:FTT_1315c.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci FTUL177416:GNBP-1340-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q5NFC4.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SCHU S4 / Schu 4.

Entry informationi

Entry nameiG6PI_FRATT
AccessioniPrimary (citable) accession number: Q5NFC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: February 1, 2005
Last modified: June 11, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi