Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5NF76

- PGK_FRATT

UniProt

Q5NF76 - PGK_FRATT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361SubstrateUniRule annotation
Binding sitei113 – 1131SubstrateUniRule annotation
Binding sitei146 – 1461SubstrateUniRule annotation
Binding sitei197 – 1971ATPUniRule annotation
Binding sitei319 – 3191ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi345 – 3484ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciFTUL177416:GNBP-1398-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:FTT_1367c
OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Taxonomic identifieri177416 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
ProteomesiUP000001174: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 392392Phosphoglycerate kinasePRO_1000057994Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi177416.FTT_1367c.

Structurei

Secondary structure

1
392
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 83
Beta strandi15 – 195
Beta strandi30 – 323
Helixi35 – 395
Helixi41 – 5010
Beta strandi53 – 575
Helixi70 – 723
Helixi75 – 8511
Beta strandi89 – 946
Turni95 – 973
Beta strandi106 – 1094
Helixi112 – 1143
Turni116 – 1216
Helixi123 – 1319
Beta strandi134 – 1385
Helixi141 – 1433
Turni149 – 1524
Helixi153 – 1575
Beta strandi158 – 1636
Helixi165 – 17814
Beta strandi183 – 19210
Helixi194 – 20411
Turni205 – 2073
Beta strandi209 – 2157
Helixi216 – 2249
Helixi236 – 2383
Helixi239 – 25113
Beta strandi260 – 26910
Beta strandi275 – 2784
Helixi279 – 2813
Beta strandi287 – 2915
Helixi293 – 30513
Beta strandi307 – 3126
Helixi321 – 3233
Helixi325 – 33713
Beta strandi339 – 3457
Helixi346 – 3549
Helixi358 – 3603
Beta strandi361 – 3655
Helixi369 – 3757
Helixi381 – 3888

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4EHJX-ray2.71A/B1-392[»]
4FEYX-ray2.30A1-392[»]
ProteinModelPortaliQ5NF76.
SMRiQ5NF76. Positions 2-390.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate bindingUniRule annotation
Regioni59 – 624Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5NF76-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSFLTLKDVD LKDKKVLVRV DFNVPVKDGK VTSKVRIEAA IPTIQYILDQ
60 70 80 90 100
GGAVILMSHL GRPTEGEYDS QFSLEPVAKA LSEIINKPVK FAKDWLDGVD
110 120 130 140 150
VKAGEIVMCE NVRFNSGEKK STDDLSKKIA SLGDVFVMDA FATAHRAQAS
160 170 180 190 200
TYGVAKYIPV ACAGILLTNE IQALEKALKS PKKPMAAIVG GSKVSTKLSV
210 220 230 240 250
LNNLLDKVEI LIVGGGIANT FIKAEGFDVG NSLYEQDLVA EATEILAKAK
260 270 280 290 300
ALGVNIPVPV DVRVAKEFSE NAQAIIKKVS DVVADEMILD IGPESQKIIA
310 320 330 340 350
ELLKSANTIL WNGPVGVFEF DNFAEGTKAL SLAIAQSHAF SVAGGGDTIA
360 370 380 390
AIEKFGIKDQ VSYISTAGGA FLEFLEGKKL PAIEILKEKA IR
Length:392
Mass (Da):41,937
Last modified:February 1, 2005 - v1
Checksum:i15AEE0E9ED62DFD2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ749949 Genomic DNA. Translation: CAG46000.1.
RefSeqiYP_170316.1. NC_006570.2.

Genome annotation databases

EnsemblBacteriaiCAG46000; CAG46000; FTT_1367c.
GeneIDi3191360.
KEGGiftu:FTT_1367c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ749949 Genomic DNA. Translation: CAG46000.1 .
RefSeqi YP_170316.1. NC_006570.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4EHJ X-ray 2.71 A/B 1-392 [» ]
4FEY X-ray 2.30 A 1-392 [» ]
ProteinModelPortali Q5NF76.
SMRi Q5NF76. Positions 2-390.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 177416.FTT_1367c.

Protocols and materials databases

DNASUi 3191360.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAG46000 ; CAG46000 ; FTT_1367c .
GeneIDi 3191360.
KEGGi ftu:FTT_1367c.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci FTUL177416:GNBP-1398-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SCHU S4 / Schu 4.

Entry informationi

Entry nameiPGK_FRATT
AccessioniPrimary (citable) accession number: Q5NF76
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 1, 2005
Last modified: October 29, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3