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Protein

Acyl carrier protein

Gene

acpP

Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Carrier of the growing fatty acid chain in fatty acid biosynthesis.UniRule annotationSAAS annotation

Pathwayi: fatty acid biosynthesis

This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Fatty acid biosynthesisUniRule annotationSAAS annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciFTUL177416:GNBP-1407-MONOMER.
UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl carrier proteinUniRule annotation
Short name:
ACPUniRule annotation
Gene namesi
Name:acpPUniRule annotationImported
Ordered Locus Names:FTT_1376Imported
ORF Names:BZ14_1407Imported
OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)Imported
Taxonomic identifieri177416 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
Proteomesi
  • UP000001174 Componenti: Chromosome
  • UP000031862 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei52 – 521O-(pantetheine 4'-phosphoryl)serineUniRule annotation

Post-translational modificationi

4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.UniRule annotation
4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.UniRule annotation

Keywords - PTMi

PhosphopantetheineUniRule annotation, PhosphoproteinUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi177416.FTT_1376.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 8971Acyl carrierInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 acyl carrier domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105VNB. Bacteria.
COG0236. LUCA.
HOGENOMiHOG000178184.
KOiK02078.
OMAiENEFGVQ.
OrthoDBiEOG6MWNJM.

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
HAMAPiMF_01217. Acyl_carrier.
InterProiIPR003231. Acyl_carrier.
IPR009081. PP-bd_ACP.
IPR006162. Ppantetheine_attach_site.
[Graphical view]
PfamiPF00550. PP-binding. 1 hit.
[Graphical view]
ProDomiPD000887. PD000887. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF47336. SSF47336. 1 hit.
TIGRFAMsiTIGR00517. acyl_carrier. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5NF67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTHNEDSKK NNADEKAKIF SRVNHIIVEQ LGVKEEDLKP EASFIDDLGA
60 70 80 90
DSLDTVELVM ALEEEFDTEI PDEDAEKIRT VKDVYDYIES KDVG
Length:94
Mass (Da):10,660
Last modified:February 1, 2005 - v1
Checksum:i9392F7F4A5EBC07F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP010290 Genomic DNA. Translation: AJI69795.1.
AJ749949 Genomic DNA. Translation: CAG46009.1.
RefSeqiWP_003025404.1. NZ_CP010290.1.
YP_170325.1. NC_006570.2.

Genome annotation databases

EnsemblBacteriaiAJI69795; AJI69795; BZ14_1407.
CAG46009; CAG46009; FTT_1376.
GeneIDi3192405.
KEGGiftu:FTT_1376.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP010290 Genomic DNA. Translation: AJI69795.1.
AJ749949 Genomic DNA. Translation: CAG46009.1.
RefSeqiWP_003025404.1. NZ_CP010290.1.
YP_170325.1. NC_006570.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi177416.FTT_1376.

Protocols and materials databases

DNASUi3192405.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAJI69795; AJI69795; BZ14_1407.
CAG46009; CAG46009; FTT_1376.
GeneIDi3192405.
KEGGiftu:FTT_1376.

Phylogenomic databases

eggNOGiENOG4105VNB. Bacteria.
COG0236. LUCA.
HOGENOMiHOG000178184.
KOiK02078.
OMAiENEFGVQ.
OrthoDBiEOG6MWNJM.

Enzyme and pathway databases

UniPathwayiUPA00094.
BioCyciFTUL177416:GNBP-1407-MONOMER.

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
HAMAPiMF_01217. Acyl_carrier.
InterProiIPR003231. Acyl_carrier.
IPR009081. PP-bd_ACP.
IPR006162. Ppantetheine_attach_site.
[Graphical view]
PfamiPF00550. PP-binding. 1 hit.
[Graphical view]
ProDomiPD000887. PD000887. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF47336. SSF47336. 1 hit.
TIGRFAMsiTIGR00517. acyl_carrier. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SCHU S4Imported and SCHU S4 / Schu 4Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SCHU S4Imported and SHU-S4Imported.

Entry informationi

Entry nameiQ5NF67_FRATT
AccessioniPrimary (citable) accession number: Q5NF67
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: July 6, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.