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Q5NET6

- Q5NET6_FRATT

UniProt

Q5NET6 - Q5NET6_FRATT

Protein
Submitted name:

Isocitrate dehydrogenase

Gene

idh

Organism
Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Feb 2005)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei152 – 1521SubstrateUniRule annotation
    Sitei262 – 2621Critical for catalysisUniRule annotation
    Metal bindingi357 – 3571Magnesium or manganese
    Sitei427 – 4271Critical for catalysisUniRule annotation
    Binding sitei554 – 5541SubstrateUniRule annotation
    Metal bindingi555 – 5551Magnesium or manganese
    Metal bindingi559 – 5591Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciFTUL177416:GNBP-1564-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
    Gene namesi
    Name:idhImported
    Ordered Locus Names:FTT_1526cImported
    OrganismiFrancisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)Imported
    Taxonomic identifieri177416 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
    ProteomesiUP000001174: Chromosome

    Interactioni

    Protein-protein interaction databases

    IntActiQ5NET6. 2 interactions.
    STRINGi177416.FTT_1526c.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5NET6.
    SMRiQ5NET6. Positions 12-747.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni139 – 1468Substrate bindingUniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiEEQRIGD.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5NET6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKFYLQEIFM HKIFYTFTDE APALATGSFL PIVESFTKVA DIELETKDIS    50
    LSARILANFN DYLTAEQKCS DDLAILGELA KTPDANIIKL PNISASIPQL 100
    TAAIKELQSK GYKIPDYPYE PKDDKEQEIK ARYAKVLGSA VNPVLREGNS 150
    DRRVADAVKK YAEKHPHSMG EWTKDSKSHV ASMSADDFYA NEKSYIVPKA 200
    TKVKIVHIDT KGTQTVLKDN LALEEKEIID ATKISIKALR EFYKNEIAKA 250
    KKEGTLLSLH LKATMMKVSD PILFGHAVEI FFEDIFKKYA KEFKELGVNP 300
    RNGWGDAVEK IKQLPQELQD KINADIEKVF AKQPDIAMVN SNKGITNLNV 350
    PSDVIIDASM PAAIRSSGKM WNKDGKLQDM KAMIPDRCYA GVYAATIDFC 400
    KENGAFDVAT MGDVSNVGLM AKKAEEYGSH DKTFEIQADG KVEVIDAEGN 450
    VIFEHQVEKG DIWRACQTKD IAVKDWVKLV VNRAKITQNP AIFWLDSKRA 500
    HDRNLIAKVN EYLTHHDTTG LDIQILSPVE ATKYSLKRMK EGKNTISVTG 550
    NVLRDYLTDL FPILELGTSA KMLSIVPLLA GGGLFETGAG GSAPKHVEQL 600
    IEENHLRWDS LGEFLALGAS LEDLAIKTRD AKIKVLAETL SQANKDFLDN 650
    DKSPRRKVGE LDTRGSHFYL AYYWVKALAE QTGNAELKAK FEPIYIELKA 700
    NKDKIVKELN DAQGKKVDVG GYYHMDRVKL DAVMRPSKTF NTILAQI 747
    Length:747
    Mass (Da):83,454
    Last modified:February 1, 2005 - v1
    Checksum:i0DA5A2486A37EEFD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ749949 Genomic DNA. Translation: CAG46159.1.
    RefSeqiYP_170456.1. NC_006570.2.

    Genome annotation databases

    EnsemblBacteriaiCAG46159; CAG46159; FTT_1526c.
    GeneIDi3192248.
    KEGGiftu:FTT_1526c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ749949 Genomic DNA. Translation: CAG46159.1 .
    RefSeqi YP_170456.1. NC_006570.2.

    3D structure databases

    ProteinModelPortali Q5NET6.
    SMRi Q5NET6. Positions 12-747.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q5NET6. 2 interactions.
    STRINGi 177416.FTT_1526c.

    Protocols and materials databases

    DNASUi 3192248.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAG46159 ; CAG46159 ; FTT_1526c .
    GeneIDi 3192248.
    KEGGi ftu:FTT_1526c.

    Phylogenomic databases

    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi EEQRIGD.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci FTUL177416:GNBP-1564-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SCHU S4 / Schu 4Imported.

    Entry informationi

    Entry nameiQ5NET6_FRATT
    AccessioniPrimary (citable) accession number: Q5NET6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 1, 2005
    Last sequence update: February 1, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3