Q5NEB8 (Q5NEB8_FRATT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase EMBL CAG46355.1
EC=4.1.1.15 EMBL CAG46355.1

Gene names

Name:	gad EMBL CAG46355.1
Ordered Locus Names:	FTT_1722c

Organism

Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4) [Reference proteome] [HAMAP] EMBL CAG46355.1

Taxonomic identifier

177416 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella › Francisella tularensis › Francisella tularensis subsp. tularensis

Protein attributes

Sequence length	448 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382 EMBL CAG46355.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5NEB8 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: 2A48F8FD23CA64D4	FASTA	448	50,815
	10 20 30 40 50 60 MALHGKKDTI DNLDFFEQSL PKFKLPLNSQ DPLEVYQEIK DELMLDGNSK QNLATFCQTE 70 80 90 100 110 120 VDDFIHKLMD DCIDKNMIDK DEYPQTAEIE SRCVNILANL WNSSAENAIG CSTTGSSEAA 130 140 150 160 170 180 MLGGMAMKWR WRDKMKAQGK DYTKPNLVTG PVQVCWHKFA RYWDIELREI PMSNESLIMT 190 200 210 220 230 240 PEAVLERCDE NTIGVVPTLG VTFTGQYEPV EQVCKALDDF ERQTGVDIPV HVDAASGGFL 250 260 270 280 290 300 APFVEPELKW DFRLPRVKSI NSSGHKFGLS PLGVGWVIWA DKKYLPDDLI FNVNYLGGNM 310 320 330 340 350 360 PAFALNFSRL GGQIVAQYYN FVRLGFEGYK KVHQLCYDVA EYIAKELRKM EIFEIIHAGE 370 380 390 400 410 420 GGIPAVSWSL KATKEYSLFD ISEKVRAKGW QIAAYTMPNN REDLVVMRVL VRRGFSYDLA 430 440 QLMIRDLVAV IDSLEGKLKI LKRSSFAH

References

[1]

"The complete genome sequence of Francisella tularensis, the causative agent of tularemia." Larsson P., Oyston P.C.F., Chain P., Chu M.C., Duffield M., Fuxelius H.-H., Garcia E., Haelltorp G., Johansson D., Isherwood K.E., Karp P.D., Larsson E., Liu Y., Michell S., Prior J., Prior R., Malfatti S., Sjoestedt A. , Svensson K., Thompson N., Vergez L., Wagg J.K., Wren B.W., Lindler L.E., Andersson S.G.E., Forsman M., Titball R.W. Nat. Genet. 37:153-159(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SCHU S4 / Schu 4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ749949 Genomic DNA. Translation: CAG46355.1.
RefSeq	YP_170624.1. NC_006570.2.
3D structure databases
ProteinModelPortal	Q5NEB8.
SMR	Q5NEB8. Positions 13-435.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q5NEB8. 1 interaction.
STRING	177416.FTT_1722c.
Protocols and materials databases
DNASU	3191876.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAG46355; CAG46355; FTT_1722c.
GeneID	3191876.
KEGG	ftu:FTT_1722c.
Phylogenomic databases
HOGENOM	HOG000070228.
KO	K01580.
OMA	WESGHSS.
ProtClustDB	CLSK935148.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q5NEB8_FRATT

Accession

Primary (citable) accession number: Q5NEB8

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)