Reviewed, UniProtKB/Swiss-Prot Q5NDL9 (AER61_CANFA)

Names and origin

Protein names

Recommended name:
    Uncharacterized glycosyltransferase AER61
    EC=2.4.-.-

Gene names

Name:

AER61

Organism

Canis familiaris (Dog)

Taxonomic identifier

9615 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Caniformia › Canidae › Canis

Protein attributes

Sequence length	527 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Secreted Potential.
Sequence similarities	Belongs to the glycosyltransferase 61 family.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Molecular function	Transferase
PTM	Glycoprotein
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 17	17	Potential
	Chain	18 – 527	510	Uncharacterized glycosyltransferase AER61		PRO_0000301971
Regions
	Motif	524 – 527	4	Prevents secretion from ER Potential
Amino acid modifications
	Glycosylation	354	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5NDL9-1 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: DA5DE507862BB6AA	FASTA	527	61,670
	10 20 30 40 50 60 MLKLLVLGVL LHDVSLSGQD EAPPKADGIP GEPLFNYASI RLPEEHIPFF LHNNRHIATV 70 80 90 100 110 120 CKKDSHCPYK KHLENLKYCW GYEKSCKPEF RFGYPVCTYI DMGWTDTLES AQDIFWKQAD 130 140 150 160 170 180 FGYAGERLEE LHVLCQPEEP HDSSLLCSRY LQYCRAANLY LDLRNIKRNH DRFKEDFFQS 190 200 210 220 230 240 GEIGGHCTLD TQTLLSEGQR KSPLQSWFAE LQSYTELNFR PIEDAKCDVV IEKPTYFMKL 250 260 270 280 290 300 DAGVNMYHHF CDFVNLYITQ HVNNSFSTDV YIVMWDTSSY GYGDLFSDTW KAFTDYDVIH 310 320 330 340 350 360 LKTYDSKRVC FKEAVFSLLP RMRYGLFYNT PLISGCQNTG LFRAFSQHVL HRLNITQEGP 370 380 390 400 410 420 KDGKIRVTIL ARSTEYRKIL NQNELVNALK TVSTLEVQIV DYKYKELGFL DQLRITHNTD 430 440 450 460 470 480 IFIGMHGAGL THLLFLPDWA AVFELYNCED ERCYLDLARL RGVHYITWRR QNKVFPQDKG 490 500 510 520 HHPTLGEHPK FTNYSFDVEE FMYLVLQAAD HVLQHPKWPF KKKRDEL

References

[1]	"Phylogeny of xylosyltransferases." Kiefer-Meyer M.C., Pagny S., Durambure G., Faye L., Gomord V., Mollicone R., Oriol R. Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ868227 mRNA. Translation: CAI30562.1.
RefSeq	NP_001009187.1.
UniGene	Cfa.16220
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT61. Glycosyltransferase Family 61.
Genome annotation databases
Ensembl	ENSCAFT00000010590; ENSCAFP00000009819; ENSCAFG00000006563; Canis familiaris. [Genome view]
GeneID	494221.
KEGG	cfa:494221.
Organism-specific databases
CTD	494221.
Phylogenomic databases
HOVERGEN	Q5NDL9.
OMA	HRLNITQ
OrthoDB	EOG9RR941
Family and domain databases
InterPro	IPR007657. Glycosyltransferase_AER61. [Graphical view]
Pfam	PF04577. DUF563. 1 hit. [Graphical view]
PROSITE	PS00014. ER_TARGET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AER61_CANFA

Accession

Primary (citable) accession number: Q5NDL9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	February 1, 2005
Last modified:	November 24, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)