Q5NDE5 (AGO61_DANRE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized glycosyltransferase AGO61
EC=2.4.-.-

Gene names

Name:	ago61
ORF Names:	im:7153239, zgc:112079

Organism

Danio rerio (Zebrafish) (Brachydanio rerio)

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	578 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Secreted Potential.
Sequence similarities	Belongs to the glycosyltransferase 61 family.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Molecular function	Transferase
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential
	Chain	26 – 578	553	Uncharacterized glycosyltransferase AGO61		PRO_0000249019
Regions
	Compositional bias	279 – 283	5	Poly-Glu
Amino acid modifications
	Glycosylation	98	1	N-linked (GlcNAc...) Potential
	Glycosylation	275	1	N-linked (GlcNAc...) Potential
	Glycosylation	541	1	N-linked (GlcNAc...) Potential
Experimental info
	Sequence conflict	282 – 283	2	Missing in AAH95667. Ref.2
	Sequence conflict	389	1	Y → H in AAH95667. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q5NDE5 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: AEDF250FDC685D23	FASTA	578	67,056
	10 20 30 40 50 60 MNLPAVLNGL LVSVVAALLW KYVRLVEHTS QLEEELQLTR QSQEFSQVRI DYHGALLALQ 70 80 90 100 110 120 EHGTRMVCTG KMHTDRICRF DYLCYCTEAE EFVFFHSNAS VMLPNLGSRR FQPALLDLSS 130 140 150 160 170 180 VEDHNTQYFN FLELPAAALK FMPKPVFVPD VTLILNRFNP DNLMHIFHDD LLPVYYTMQQ 190 200 210 220 230 240 YSDLDDEARL VFMEGWGEGA HFDLYRLLSS KQPLLKDQLK TFGKLMCFTK SYVGLSKMTT 250 260 270 280 290 300 WYQYGFVQPQ GPKANILISG NEIRQFASFL MERLNITREE EEEDDDYIVV FKRTTNRLIL 310 320 330 340 350 360 NEAELLLALA QEFQMRTVTV SLEEQSFDNI IQIISRAAML VSMHGAQMIT SMFLPRGAAV 370 380 390 400 410 420 VELFPYGVNP EQYTPYKTLA SLPGMDLQYV AWRNTMEENT VTFPDRPWDQ GGIVHLEKEE 430 440 450 460 470 480 QERILASKEV PRHLCCRNPE WLFRIYQDTT VDLASFLDVL RDGLKKLNLK KAKVASTVHP 490 500 510 520 530 540 GRVREPKCQT SVQATNEAKL SVSWQIPWNL KYLKVKEVKY EVWIQEQGEN TYMPYILPHQ 550 560 570 NYTFSENIKP FTTYLVWVRC IFNKNLLGPF ADVLICKT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Phylogeny of xylosyltransferases." Kiefer-Meyer M.C., Pagny S., Durambure G., Faye L., Gomord V., Mollicone R., Oriol R. Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ868539 mRNA. Translation: CAI30873.1. BC095667 mRNA. Translation: AAH95667.1.
IPI	IPI00993827.
RefSeq	NP_001012384.1. NM_001012384.1.
UniGene	Dr.91306.
3D structure databases
ProteinModelPortal	Q5NDE5.
ModBase	Search...
Protein family/group databases
CAZy	GT61. Glycosyltransferase Family 61.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000010739; ENSDARP00000005523; ENSDARG00000010941.
GeneID	497644.
KEGG	dre:497644.
NMPDR	fig|7955.3.peg.31897.
Organism-specific databases
ZFIN	ZDB-GENE-050522-242. zgc:112079.
Phylogenomic databases
GeneTree	ENSGT00390000018454.
HOGENOM	HBG283724.
HOVERGEN	HBG054852.
InParanoid	Q5NDE5.
OMA	FPYAVNP.
OrthoDB	EOG4TQM8N.
PhylomeDB	Q5NDE5.
Gene expression databases
Bgee	Q5NDE5.
Family and domain databases
InterPro	IPR003961. Fibronectin_type3. IPR007657. Glycosyltransferase_AER61. IPR013783. Ig-like_fold. [Graphical view]
Gene3D	G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
Pfam	PF04577. DUF563. 1 hit. [Graphical view]
SMART	SM00060. FN3. 1 hit. [Graphical view]
SUPFAM	SSF49265. FN_III-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

AGO61_DANRE

Accession

Primary (citable) accession number: Q5NDE5
Secondary accession number(s): Q502K0

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 5, 2006
Last sequence update:	February 1, 2005
Last modified:	October 19, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program