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Protein
Submitted name:

SPARC

Gene

Sparc

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
SPARCImported
Gene namesi
Name:SparcImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:98373. Sparc.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500426029818 – 301Sequence analysisAdd BLAST284

Proteomic databases

MaxQBiQ5NCU4.
PaxDbiQ5NCU4.
PRIDEiQ5NCU4.

Expressioni

Gene expression databases

BgeeiENSMUSG00000018593.
ExpressionAtlasiQ5NCU4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ5NCU4.
SMRiQ5NCU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini92 – 149Kazal-likeInterPro annotationAdd BLAST58

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4004. Eukaryota.
ENOG41101WW. LUCA.
GeneTreeiENSGT00510000046787.
HOGENOMiHOG000088654.
HOVERGENiHBG002746.

Family and domain databases

InterProiView protein in InterPro
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR003645. Fol_N.
IPR015369. Follistatin/Osteonectin_EGF.
IPR002350. Kazal_dom.
IPR001999. Osteonectin_CS.
IPR019577. SPARC/Testican_Ca-bd-dom.
PfamiView protein in Pfam
PF09289. FOLN. 1 hit.
PF00050. Kazal_1. 1 hit.
PF10591. SPARC_Ca_bdg. 1 hit.
SMARTiView protein in SMART
SM00274. FOLN. 1 hit.
SM00280. KAZAL. 1 hit.
SUPFAMiSSF100895. SSF100895. 1 hit.
SSF47473. SSF47473. 1 hit.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 1 hit.
PS51465. KAZAL_2. 1 hit.
PS00612. OSTEONECTIN_1. 1 hit.
PS00613. OSTEONECTIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5NCU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAWIFFLLC LAGRALAAPQ TEVAEEIVEE ETVVEETGVP VGANPVQVEM
60 70 80 90 100
GEFEDGAEET VEEVVADNPC QNHHCKHGKV CELDESNTPM CVCQDPTSCP
110 120 130 140 150
APIGEFEKVC SNDNKTFDSS CHFFATKCTL EGTKKGHKLH LDYIGPCKYI
160 170 180 190 200
APCLDSELTE FPLRMRDWLK NVLVTLYERD EGNNLLTEKQ KLRVKKIHEN
210 220 230 240 250
EKRLEAGDHP VELLARDFEK NYNMYIFPVH WQFGQLDQHP IDGYLSHTEL
260 270 280 290 300
APLRAPLIPM EHCTTRFFET CDLDNDKYIA LEEWAGCFGI KEQDINKDLV

I
Length:301
Mass (Da):34,322
Last modified:February 5, 2008 - v1
Checksum:i30AE9E448F5948A2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596207 Genomic DNA. No translation available.
AL772268 Genomic DNA. No translation available.
RefSeqiNP_001277746.1. NM_001290817.1.
UniGeneiMm.291442.

Genome annotation databases

EnsembliENSMUST00000108858; ENSMUSP00000104486; ENSMUSG00000018593.
GeneIDi20692.
UCSCiuc007izi.3. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ5NCU4_MOUSE
AccessioniPrimary (citable) accession number: Q5NCU4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: August 30, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported