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Protein

Trafficking protein particle complex subunit 1

Gene

Trappc1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May play a role in vesicular transport from endoplasmic reticulum to Golgi.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ER-Golgi transport, Transport

Enzyme and pathway databases

ReactomeiR-MMU-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Trafficking protein particle complex subunit 1
Gene namesi
Name:Trappc1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1098727. Trappc1.

Subcellular locationi

GO - Cellular componenti

  • cis-Golgi network Source: InterPro
  • endoplasmic reticulum Source: UniProtKB-SubCell
  • Golgi apparatus Source: UniProtKB-SubCell
  • TRAPP complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 145145Trafficking protein particle complex subunit 1PRO_0000211563Add
BLAST

Proteomic databases

EPDiQ5NCF2.
MaxQBiQ5NCF2.
PaxDbiQ5NCF2.
PRIDEiQ5NCF2.

PTM databases

PhosphoSiteiQ5NCF2.

Expressioni

Gene expression databases

BgeeiQ5NCF2.
CleanExiMM_TRAPPC1.
ExpressionAtlasiQ5NCF2. baseline and differential.
GenevisibleiQ5NCF2. MM.

Interactioni

Subunit structurei

Part of the multisubunit TRAPP (transport protein particle) complex.By similarity

Protein-protein interaction databases

BioGridi232834. 2 interactions.
IntActiQ5NCF2. 1 interaction.
STRINGi10090.ENSMUSP00000099661.

Structurei

Secondary structure

1
145
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 97Combined sources
Beta strandi15 – 228Combined sources
Helixi31 – 5222Combined sources
Beta strandi61 – 655Combined sources
Beta strandi70 – 756Combined sources
Beta strandi81 – 866Combined sources
Helixi94 – 1029Combined sources
Helixi105 – 1084Combined sources
Turni109 – 1113Combined sources
Helixi124 – 13411Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2J3TX-ray2.40C1-145[»]
ProteinModelPortaliQ5NCF2.
SMRiQ5NCF2. Positions 2-142.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5NCF2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3368. Eukaryota.
ENOG4111X41. LUCA.
GeneTreeiENSGT00510000047863.
HOGENOMiHOG000172118.
HOVERGENiHBG056032.
InParanoidiQ5NCF2.
OMAiFYETPAN.
OrthoDBiEOG7GXPD7.
TreeFamiTF323681.

Family and domain databases

InterProiIPR011012. Longin-like_dom.
IPR007233. TRAPPC.
[Graphical view]
PANTHERiPTHR23249. PTHR23249. 1 hit.
PfamiPF04099. Sybindin. 1 hit.
[Graphical view]
SMARTiSM01399. Sybindin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5NCF2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVHNLYLFD RNGVCLHYSE WHRKKQAGIP KEEEYKLMYG MLFSIRSFVS
60 70 80 90 100
KMSPLDMKDG FLSFQTSRYK LHYYETPTGI KVVMNTDLGV GPIRDVLHHI
110 120 130 140
YSALYVEFVV KNPLCPLGQT VQSELFRSRL DSYVRSLPFF SARAG
Length:145
Mass (Da):16,882
Last modified:February 1, 2005 - v1
Checksum:i7C8C9FCC1118CDC7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645527 Genomic DNA. Translation: CAI35255.1.
CCDSiCCDS24889.1.
RefSeqiNP_001019377.1. NM_001024206.2.
UniGeneiMm.28073.

Genome annotation databases

EnsembliENSMUST00000102601; ENSMUSP00000099661; ENSMUSG00000049299.
ENSMUST00000102602; ENSMUSP00000099662; ENSMUSG00000049299.
GeneIDi245828.
KEGGimmu:245828.
UCSCiuc007jpq.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645527 Genomic DNA. Translation: CAI35255.1.
CCDSiCCDS24889.1.
RefSeqiNP_001019377.1. NM_001024206.2.
UniGeneiMm.28073.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2J3TX-ray2.40C1-145[»]
ProteinModelPortaliQ5NCF2.
SMRiQ5NCF2. Positions 2-142.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi232834. 2 interactions.
IntActiQ5NCF2. 1 interaction.
STRINGi10090.ENSMUSP00000099661.

PTM databases

PhosphoSiteiQ5NCF2.

Proteomic databases

EPDiQ5NCF2.
MaxQBiQ5NCF2.
PaxDbiQ5NCF2.
PRIDEiQ5NCF2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000102601; ENSMUSP00000099661; ENSMUSG00000049299.
ENSMUST00000102602; ENSMUSP00000099662; ENSMUSG00000049299.
GeneIDi245828.
KEGGimmu:245828.
UCSCiuc007jpq.2. mouse.

Organism-specific databases

CTDi58485.
MGIiMGI:1098727. Trappc1.

Phylogenomic databases

eggNOGiKOG3368. Eukaryota.
ENOG4111X41. LUCA.
GeneTreeiENSGT00510000047863.
HOGENOMiHOG000172118.
HOVERGENiHBG056032.
InParanoidiQ5NCF2.
OMAiFYETPAN.
OrthoDBiEOG7GXPD7.
TreeFamiTF323681.

Enzyme and pathway databases

ReactomeiR-MMU-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.

Miscellaneous databases

EvolutionaryTraceiQ5NCF2.
NextBioi386942.
PROiQ5NCF2.
SOURCEiSearch...

Gene expression databases

BgeeiQ5NCF2.
CleanExiMM_TRAPPC1.
ExpressionAtlasiQ5NCF2. baseline and differential.
GenevisibleiQ5NCF2. MM.

Family and domain databases

InterProiIPR011012. Longin-like_dom.
IPR007233. TRAPPC.
[Graphical view]
PANTHERiPTHR23249. PTHR23249. 1 hit.
PfamiPF04099. Sybindin. 1 hit.
[Graphical view]
SMARTiSM01399. Sybindin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Brown adipose tissue, Kidney, Liver, Lung, Pancreas, Spleen and Testis.

Entry informationi

Entry nameiTPPC1_MOUSE
AccessioniPrimary (citable) accession number: Q5NCF2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: February 1, 2005
Last modified: May 11, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.