Q5NBY1 (Q5NBY1_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate receptor, ionotropic, AMPA1 (Alpha 1) EMBL CAI35291.1

Submitted name:
Uncharacterized protein Ensembl ENSMUSP00000117339

Gene names

Name:	Gria1 Ensembl ENSMUSP00000117339 MGI 95808
ORF Names:	RP23-102H8.1-005 EMBL CAI35291.1

Organism

Mus musculus (Mouse) EMBL CAI35291.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	692 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Cell junction Cell membrane SAAS SAAS001508 Membrane Postsynaptic cell membrane SAAS SAAS001508 Synapse
Domain	Transmembrane Transmembrane helix SAAS SAAS001508
Molecular function	Ionic channel Ligand-gated ion channel SAAS SAAS001508 Receptor SAAS SAAS001508 EMBL CAI35291.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	synaptic transmission Inferred from genetic interaction. Source: MGI
Cellular component	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Inferred from direct assay. Source: MGI cell junction Inferred from electronic annotation. Source: UniProtKB-KW membrane fraction Inferred from direct assay. Source: MGI outer membrane-bounded periplasmic space Inferred from electronic annotation. Source: InterPro postsynaptic membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	extracellular-glutamate-gated ion channel activity Inferred from electronic annotation. Source: InterPro ionotropic glutamate receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAI35291.1 Ensembl ENSMUSP00000117339

Sequences

	Sequence		Length	Mass (Da)
	Q5NBY1 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: 6E9306851F931929	FASTA	692	77,028
	10 20 30 40 50 60 IVKLEKNGIG YHYILANLGF MDIDLNKFKE SGANVTGFQL VNYTDTIPAR IMQQWRTSDA 70 80 90 100 110 120 RDHTRVDWKR PKYTSALTYD GVKVMAEAFQ SLRRQRIDIS RRGNAGDCLA NPAVPWGQGI 130 140 150 160 170 180 DIQRALQQVR FEGLTGNVQF NEKGRRTNYT LHVIEMKHDG IRKIGYWNED DKFVPAATDA 190 200 210 220 230 240 QAGGDNSSVQ NRTYIVTTIL EDPYVMLKKN ANQFEGNDRY EGYCVELAAE IAKHVGYSYR 250 260 270 280 290 300 LEIVSDGKYG ARDPDTKAWN GMVGELVYGR ADVAVAPLTI TLVREEVIDF SKPFMSLGIS 310 320 330 340 350 360 IMIKKPQKSK PGVFSFLDPL AYEIWMCIVF AYIGVSVVLF LVSRFSPYEW HSEEFEEGRD 370 380 390 400 410 420 QTTSDQSNEF GIFNSLWFSL GAFMQQGCDI SPRSLSGRIV GGVWWFFTLI IISSYTANLA 430 440 450 460 470 480 AFLTVERMVS PIESAEDLAK QTEIAYGTLE AGSTKEFFRR SKIAVFEKMW TYMKSAEPSV 490 500 510 520 530 540 FVRTTEEGMI RVRKSKGKYA YLLESTMNEY IEQRKPCDTM KVGGNLDSKG YGIATPKGSA 550 560 570 580 590 600 LRNPVNLAVL KLNEQGLLDK LKNKWWYDKG ECGSGGGDSK DKTSALSLSN VAGVFYILIG 610 620 630 640 650 660 GLGLAMLVAL IEFCYKSRSE SKRMKGFCLI PQQSINEAIR TSTLPRNSGA GASGGSGSGE 670 680 690 NGRVVSQDFP KSMQSIPCMS HSSGMPLGAT GL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Mouse Genome Sequencing Consortium Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6 Ensembl ENSMUSP00000117339.
[2]	Tromans A. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000117339.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL663055 Genomic DNA. No translation available. AL954821 Genomic DNA. No translation available. BX248119 Genomic DNA. No translation available. AL672177 Genomic DNA. Translation: CAI35291.1.
IPI	IPI00407939.
UniGene	Mm.4920.
3D structure databases
ProteinModelPortal	Q5NBY1.
SMR	Q5NBY1. Positions 1-616.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q5NBY1. 1 interaction.
STRING	Q5NBY1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000136007; ENSMUSP00000117339; ENSMUSG00000020524.
Organism-specific databases
MGI	MGI:95808. Gria1.
Phylogenomic databases
HOVERGEN	HBG051839.
Gene expression databases
ArrayExpress	Q5NBY1.
Bgee	Q5NBY1.
Genevestigator	Q5NBY1.
Family and domain databases
InterPro	IPR001828. ANF_lig-bd_rcpt. IPR019594. Glu_rcpt_Glu/Gly-bd. IPR001320. Iontro_glu_rcpt. IPR001508. NMDA_rcpt. IPR001638. SBP_bac_3. [Graphical view]
Pfam	PF01094. ANF_receptor. 1 hit. PF00060. Lig_chan. 1 hit. PF00497. SBP_bac_3. 1 hit. [Graphical view]
PRINTS	PR00177. NMDARECEPTOR.
SMART	SM00918. Lig_chan-Glu_bd. 1 hit. SM00079. PBPe. 1 hit. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

Q5NBY1_MOUSE

Accession

Primary (citable) accession number: Q5NBY1

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	November 16, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)