ID   C3H6_ORYSJ              Reviewed;         476 AA.
AC   Q5NAW2; A0A0P0V0L0; Q0JNX7; Q5NAW3; Q6IVC4;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 2.
DT   27-MAR-2024, entry version 100.
DE   RecName: Full=Zinc finger CCCH domain-containing protein 6;
DE            Short=OsC3H6;
DE   AltName: Full=Zinc finger CCCH domain-containing protein ZFN-like 1;
GN   OrderedLocusNames=Os01g0258700, LOC_Os01g15460;
GN   ORFNames=P0462H08.27-1, P0462H08.27-2;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
RC   STRAIN=cv. Aichi asahi;
RA   Meng X.-B., Lin R.-M., Wang M., Zhao W.-S., Zhang S.-H., Peng Y.-L.;
RT   "Molecular cloning and expression of a Magnaporthe grisea induced cDNA
RT   encoding a zinc-finger transcription factor.";
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447438; DOI=10.1038/nature01184;
RA   Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA   Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA   Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA   Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA   Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA   Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA   Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA   Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA   Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA   Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA   Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA   Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA   Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT   "The genome sequence and structure of rice chromosome 1.";
RL   Nature 420:312-316(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [7]
RP   NOMENCLATURE.
RX   PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA   Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT   "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL   BMC Genomics 9:44-44(2008).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1;
CC         IsoId=Q5NAW2-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q5NAW2-2; Sequence=VSP_013559;
CC       Name=3;
CC         IsoId=Q5NAW2-3; Sequence=VSP_013560;
CC   -!- MISCELLANEOUS: [Isoform 2]: May be due to intron retention.
CC       {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 3]: May be due to intron retention.
CC       {ECO:0000305}.
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DR   EMBL; AY573063; AAT35591.1; -; mRNA.
DR   EMBL; AY620413; AAT28673.1; -; mRNA.
DR   EMBL; AP002525; BAD81401.1; -; Genomic_DNA.
DR   EMBL; AP002525; BAD81402.1; -; Genomic_DNA.
DR   EMBL; AP008207; BAF04551.1; -; Genomic_DNA.
DR   EMBL; AP014957; BAS71408.1; -; Genomic_DNA.
DR   EMBL; AK111633; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AK111727; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AK111903; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_015651248.1; XM_015795762.1.
DR   AlphaFoldDB; Q5NAW2; -.
DR   STRING; 39947.Q5NAW2; -.
DR   PaxDb; 39947-Q5NAW2; -.
DR   EnsemblPlants; Os01t0258700-01; Os01t0258700-01; Os01g0258700. [Q5NAW2-1]
DR   GeneID; 4326236; -.
DR   Gramene; Os01t0258700-01; Os01t0258700-01; Os01g0258700. [Q5NAW2-1]
DR   KEGG; osa:4326236; -.
DR   eggNOG; KOG1677; Eukaryota.
DR   HOGENOM; CLU_033292_1_1_1; -.
DR   InParanoid; Q5NAW2; -.
DR   OMA; AYTGPYL; -.
DR   OrthoDB; 33612at2759; -.
DR   Proteomes; UP000000763; Chromosome 1.
DR   Proteomes; UP000059680; Chromosome 1.
DR   ExpressionAtlas; Q5NAW2; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   Gene3D; 2.30.30.1190; -; 1.
DR   Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 2.
DR   InterPro; IPR000571; Znf_CCCH.
DR   InterPro; IPR036855; Znf_CCCH_sf.
DR   PANTHER; PTHR12506; PROTEIN PHOSPHATASE RELATED; 1.
DR   PANTHER; PTHR12506:SF41; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 58; 1.
DR   Pfam; PF00642; zf-CCCH; 5.
DR   SMART; SM00356; ZnF_C3H1; 5.
DR   SUPFAM; SSF90229; CCCH zinc finger; 5.
DR   PROSITE; PS50103; ZF_C3H1; 5.
DR   Genevisible; Q5NAW2; OS.
PE   2: Evidence at transcript level;
KW   Alternative splicing; DNA-binding; Metal-binding; Nucleus;
KW   Reference proteome; Repeat; Zinc; Zinc-finger.
FT   CHAIN           1..476
FT                   /note="Zinc finger CCCH domain-containing protein 6"
FT                   /id="PRO_0000213922"
FT   ZN_FING         59..87
FT                   /note="C3H1-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         108..136
FT                   /note="C3H1-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         153..181
FT                   /note="C3H1-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         307..335
FT                   /note="C3H1-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         353..381
FT                   /note="C3H1-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          1..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          290..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          456..476
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        290..304
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        457..476
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..269
FT                   /note="Missing (in isoform 3)"
FT                   /evidence="ECO:0000303|Ref.1"
FT                   /id="VSP_013560"
FT   VAR_SEQ         1..29
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12869764"
FT                   /id="VSP_013559"
FT   CONFLICT        158
FT                   /note="E -> K (in Ref. 6; AK111903)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        386
FT                   /note="S -> G (in Ref. 6; AK111727)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   476 AA;  49835 MW;  46F41CB2DC3D6A52 CRC64;
     MEQPHAAAAA AGGGEGEGGA SPDTGLEGPM WRMGLGGGGG GGGGGGGGDG DAAGRLPERP
     GEEDCVYYLR TGACGFGDRC RYNHPRDRGG TEFGGGARNA AALDYPERAG QPICEYYMKT
     GTCKFGTNCK YHHPKQDGAV LPVMLNNSGF PIRLGEKECS YYMKTGQCKF GTTCKFHHPE
     FGGVPMTPGI YPPLQSPSIA SPHPYASLAN WQMGRPPVVP GSYIPGSYTP MMLSSGMIPL
     QGWSPYPASV NPVVSGGAQQ NVQAGPVYGM GHHGSSSTIA YGGPYVPYAS STGQSSNNQQ
     EHGFPERPGQ PDCQYYMRTG DCKFGATCKY HHPRELSAPK SGYMVNSLCL PLRPGAQPCA
     YYAQNGYCRY GVACKYDHPM GTLGYSPSAL PLSDMPIAPY PIGFSIATLA PSSPSPDLRP
     EYISTKDQSV NQVTSPVAAS EPVGSILPKG VFPADTMMRA QTNTTSGGSS SPGGGR
//