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Protein

CDP-diacylglycerol--serine O-phosphatidyltransferase 3

Gene

PSS3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine.By similarity

Catalytic activityi

CDP-diacylglycerol + L-serine = CMP + (3-sn-phosphatidyl)-L-serine.

Pathwayi: phosphatidylethanolamine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes phosphatidylethanolamine from CDP-diacylglycerol.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. CDP-diacylglycerol--serine O-phosphatidyltransferase 3 (PSS3), CDP-diacylglycerol--serine O-phosphatidyltransferase 1 (PSS1), CDP-diacylglycerol--serine O-phosphatidyltransferase 2 (PSS2)
  2. Phosphatidylserine decarboxylase proenzyme 2 (PSD2), Phosphatidylserine decarboxylase proenzyme 1, mitochondrial (PSD1), Phosphatidylserine decarboxylase proenzyme 2 (PSD2)
This subpathway is part of the pathway phosphatidylethanolamine biosynthesis, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes phosphatidylethanolamine from CDP-diacylglycerol, the pathway phosphatidylethanolamine biosynthesis and in Phospholipid metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00558; UER00615.

Names & Taxonomyi

Protein namesi
Recommended name:
CDP-diacylglycerol--serine O-phosphatidyltransferase 3 (EC:2.7.8.8)
Alternative name(s):
Phosphatidylserine synthase 3
Gene namesi
Name:PSS3
Ordered Locus Names:Os01g0683500/Os01g0683550, LOC_Os01g49024
ORF Names:P0445E10.10
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei103 – 123HelicalSequence analysisAdd BLAST21
Transmembranei142 – 162HelicalSequence analysisAdd BLAST21
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21
Transmembranei260 – 280HelicalSequence analysisAdd BLAST21
Transmembranei287 – 307HelicalSequence analysisAdd BLAST21
Transmembranei359 – 379HelicalSequence analysisAdd BLAST21
Transmembranei384 – 404HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004295291 – 419CDP-diacylglycerol--serine O-phosphatidyltransferase 3Add BLAST419

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ5N8Q3.

Family and domain databases

InterProiIPR004277. PSS.
[Graphical view]
PfamiPF03034. PSS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5N8Q3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVRRRWYPP SSTAAQPSPD GGDVNTDDAD ACPSSRQQRP PSLPQHSAPI
60 70 80 90 100
HHRRRVINSI DASGEVMEYG SSNDQRMQDM EIWPSDGGGV EEYDPWTAWL
110 120 130 140 150
YKPHTVSVLL AGACLLIWAS GVLHPEITSS HDKVIPIKRG VWAMIAVFLA
160 170 180 190 200
YCTLQAPSTI LIRPHPAVWR LVHGMAVVYL VALTFLLFQK RDDARQFMKH
210 220 230 240 250
LHPGLGVELP ERSYGSDCRM YVPENPTNRF INIQETLFDE FVIAHVLGWW
260 270 280 290 300
GKAVMIRNQL LLWVLSVGFE LMELTFRHML PNFNECWWDS IILDIMICNW
310 320 330 340 350
FGIWAGMHTV RYFDGKTYEW VGLSRQPSIM GKVKRSLCQF TPAKWDKDQW
360 370 380 390 400
HPFMEPRRFI QVFCLCVGFM TVELNTFFLK FCLWIPPRNP LVVYRLILWW
410
LIAIPAIREY NTYLQDRSS
Length:419
Mass (Da):48,596
Last modified:July 9, 2014 - v2
Checksum:i449FFA638C3EA565
GO

Sequence cautioni

The sequence BAD82153 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAH91236 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003347 Genomic DNA. Translation: BAD82153.1. Sequence problems.
AP008207 Genomic DNA. Translation: BAH91236.1. Sequence problems.
AP014957 Genomic DNA. No translation available.
UniGeneiOs.77427.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003347 Genomic DNA. Translation: BAD82153.1. Sequence problems.
AP008207 Genomic DNA. Translation: BAH91236.1. Sequence problems.
AP014957 Genomic DNA. No translation available.
UniGeneiOs.77427.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

InParanoidiQ5N8Q3.

Enzyme and pathway databases

UniPathwayiUPA00558; UER00615.

Family and domain databases

InterProiIPR004277. PSS.
[Graphical view]
PfamiPF03034. PSS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPSS3_ORYSJ
AccessioniPrimary (citable) accession number: Q5N8Q3
Secondary accession number(s): C7IX41
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 7, 2016
This is version 43 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.