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Reviewed, UniProtKB/Swiss-Prot Q5N7B4 (LAC7_ORYSJ)

Last modified November 25, 2008. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Laccase-7
    EC=1.10.3.2
Alternative name(s):
    Benzenediol:oxygen oxidoreductase 7
    Urishiol oxidase 7
    Diphenol oxidase 7
Gene names
Name: LAC7
Ordered Locus Names: Os01g0850700, LOC_Os01g63190
ORF Names: P0414E03.33-1, P0529H11.22-1, OsJ_003987
OrganismOryza sativa subsp. japonica (Rice)
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length559 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Function

Lignin degradation and detoxification of lignin-derived products By similarity.

Catalytic activity

4 benzenediol + O(2) = 4 benzosemiquinone + 2 H(2)O.

Cofactor

Binds 4 copper ions per monomer By similarity.

Subcellular location

Secretedextracellular spaceapoplastPotential.

Sequence similarities

Belongs to the multicopper oxidase family.

Contains 3 plastocyanin-like domains.

Sequence caution

The sequence EAZ14162.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords

   Biological processLignin degradation
   Cellular componentApoplast
Secreted
   DomainRepeat
Signal
   LigandCopper
Metal-binding
   Molecular functionOxidoreductase
   PTMGlycoprotein

Gene Ontology (GO)

   Biological processlignin catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentapoplast

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functioncopper ion binding

Inferred from electronic annotation. Source: InterPro

laccase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2828 Potential
Chain29 – 559531Laccase-7
PRO_0000291892

Regions

Domain36 – 152117Plastocyanin-like 1
Domain163 – 316154Plastocyanin-like 2
Domain396 – 543148Plastocyanin-like 3

Sites

Metal binding861Copper 1 By similarity
Metal binding881Copper 2 By similarity
Metal binding1311Copper 2 By similarity
Metal binding1331Copper 3 By similarity
Metal binding4611Copper 4 By similarity
Metal binding4641Copper 1 By similarity
Metal binding4661Copper 3 By similarity
Metal binding5221Copper 3 By similarity
Metal binding5231Copper 4 By similarity
Metal binding5241Copper 2 By similarity
Metal binding5281Copper 4 By similarity

Amino acid modifications

Glycosylation321N-linked (GlcNAc...) Potential
Glycosylation471N-linked (GlcNAc...) Potential
Glycosylation821N-linked (GlcNAc...) Potential
Glycosylation1121N-linked (GlcNAc...) Potential
Glycosylation1201N-linked (GlcNAc...) Potential
Glycosylation1511N-linked (GlcNAc...) Potential
Glycosylation2101N-linked (GlcNAc...) Potential
Glycosylation2201N-linked (GlcNAc...) Potential
Glycosylation2571N-linked (GlcNAc...) Potential
Glycosylation2781N-linked (GlcNAc...) Potential
Glycosylation3141N-linked (GlcNAc...) Potential
Glycosylation3631N-linked (GlcNAc...) Potential
Glycosylation4431N-linked (GlcNAc...) Potential
Glycosylation4841N-linked (GlcNAc...) Potential
Glycosylation5411N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q5N7B4-1 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: E39123EF1389DDE0

FASTA55960,212
        10         20         30         40         50         60 
MVIPWCSSMM RLLWFLFALL LARSVADAAT ANYTFTVESM RVSRLCNSTD IIAVNGLLPG 

        70         80         90        100        110        120 
PMIEVNEGDA VAVEVINGSP YNLTIHWHGI LQLLTPWADG PSMVTQCPIQ PNSSYTYRFN 

       130        140        150        160        170        180 
VTGQEGTLWW HAHSSFLRAT VYGALIIRPR NGSAYPFPAP DQEVPIVLGE WWSRNVVDIE 

       190        200        210        220        230        240 
SDAVSSGQLP RESDAFTVNG VTGELYQCAN DTFTVDVQPN TTVLLRVINA GLNTHLFFKV 

       250        260        270        280        290        300 
AGHAFTVVAV DACYTANYTT DTLVLAPGHT VDALMVTNAS AGSYYMAVQA YDSLSPTTMA 

       310        320        330        340        350        360 
VTDDTTATAI VHYNTTSTKK NATPVMPTMP QSSDSATANA FYFGLRGPPS PSAPAVPTKV 

       370        380        390        400        410        420 
DVNMTIELGL GQLPCDSTQS SCSGKSVAAA MNGVSFRLPS QMSLLEAQFN RTPGVYTADF 

       430        440        450        460        470        480 
PDAPQPSGTP MVEGTKVRRL KYNSTVEIVL QNPTAFPSEN HPIHLHGFNF FVLAQGLGNF 

       490        500        510        520        530        540 
TPGNVSGYNL VDPVSRNTLA VPTGGWAVIR FVANNPGMWF FHCHLDAHVP MGLGMVFAVD 

       550 
NGTTPDSFLP PPPADLPKC 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence and structure of rice chromosome 1."
Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. expand/collapse author list , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
Nature 420:312-316(2002) [PubMed: 12447438] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed: 16100779] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana."
The rice annotation project (RAP)
Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[5]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed: 12869764] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

AP003242 Genomic DNA. Translation: BAD81779.1.
AP004072 Genomic DNA. Translation: BAD82647.1.
AP008207 Genomic DNA. Translation: BAF06729.1.
CM000138 Genomic DNA. Translation: EAZ14162.1. Sequence problems.
AK109431 mRNA. No translation available.
RefSeqNP_001044815.1.
UniGeneOs.14830

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4324802.
KEGGosa:4324802.
NMPDRfig|39947.1.peg.7577.

Organism-specific databases

GrameneQ5N7B4.

Family and domain databases

InterProIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
Gene3DG3DSA:2.60.40.420. Cupredoxin. 3 hits.
PfamPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
PROSITEPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLAC7_ORYSJ
AccessionPrimary (citable) accession number: Q5N7B4
Secondary accession number(s): A2ZZL5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: February 1, 2005
Last modified: November 25, 2008
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents