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Protein

Laccase-7

Gene

LAC7

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi86Copper 1By similarity1
Metal bindingi88Copper 2By similarity1
Metal bindingi131Copper 2By similarity1
Metal bindingi133Copper 3By similarity1
Metal bindingi461Copper 4By similarity1
Metal bindingi464Copper 1By similarity1
Metal bindingi466Copper 3By similarity1
Metal bindingi522Copper 3By similarity1
Metal bindingi523Copper 4By similarity1
Metal bindingi524Copper 2By similarity1
Metal bindingi528Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-7 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 7
Diphenol oxidase 7
Urishiol oxidase 7
Gene namesi
Name:LAC7
Ordered Locus Names:Os01g0850700, LOC_Os01g63190
ORF Names:OsJ_003987, OsJ_04091Imported, P0414E03.33-1, P0529H11.22-1
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_000029189229 – 559Laccase-7Add BLAST531

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi32N-linked (GlcNAc...)Sequence analysis1
Glycosylationi47N-linked (GlcNAc...)Sequence analysis1
Glycosylationi82N-linked (GlcNAc...)Sequence analysis1
Glycosylationi112N-linked (GlcNAc...)Sequence analysis1
Glycosylationi120N-linked (GlcNAc...)Sequence analysis1
Glycosylationi151N-linked (GlcNAc...)Sequence analysis1
Glycosylationi210N-linked (GlcNAc...)Sequence analysis1
Glycosylationi220N-linked (GlcNAc...)Sequence analysis1
Glycosylationi257N-linked (GlcNAc...)Sequence analysis1
Glycosylationi278N-linked (GlcNAc...)Sequence analysis1
Glycosylationi314N-linked (GlcNAc...)Sequence analysis1
Glycosylationi363N-linked (GlcNAc...)Sequence analysis1
Glycosylationi443N-linked (GlcNAc...)Sequence analysis1
Glycosylationi484N-linked (GlcNAc...)Sequence analysis1
Glycosylationi541N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ5N7B4.

Expressioni

Gene expression databases

ExpressionAtlasiQ5N7B4. baseline and differential.
GenevisibleiQ5N7B4. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g63190.1.

Structurei

3D structure databases

ProteinModelPortaliQ5N7B4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 152Plastocyanin-like 1Add BLAST117
Domaini163 – 316Plastocyanin-like 2Add BLAST154
Domaini396 – 543Plastocyanin-like 3Add BLAST148

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ5N7B4.
OMAiIVHYNTT.
OrthoDBiEOG093605KG.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5N7B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVIPWCSSMM RLLWFLFALL LARSVADAAT ANYTFTVESM RVSRLCNSTD
60 70 80 90 100
IIAVNGLLPG PMIEVNEGDA VAVEVINGSP YNLTIHWHGI LQLLTPWADG
110 120 130 140 150
PSMVTQCPIQ PNSSYTYRFN VTGQEGTLWW HAHSSFLRAT VYGALIIRPR
160 170 180 190 200
NGSAYPFPAP DQEVPIVLGE WWSRNVVDIE SDAVSSGQLP RESDAFTVNG
210 220 230 240 250
VTGELYQCAN DTFTVDVQPN TTVLLRVINA GLNTHLFFKV AGHAFTVVAV
260 270 280 290 300
DACYTANYTT DTLVLAPGHT VDALMVTNAS AGSYYMAVQA YDSLSPTTMA
310 320 330 340 350
VTDDTTATAI VHYNTTSTKK NATPVMPTMP QSSDSATANA FYFGLRGPPS
360 370 380 390 400
PSAPAVPTKV DVNMTIELGL GQLPCDSTQS SCSGKSVAAA MNGVSFRLPS
410 420 430 440 450
QMSLLEAQFN RTPGVYTADF PDAPQPSGTP MVEGTKVRRL KYNSTVEIVL
460 470 480 490 500
QNPTAFPSEN HPIHLHGFNF FVLAQGLGNF TPGNVSGYNL VDPVSRNTLA
510 520 530 540 550
VPTGGWAVIR FVANNPGMWF FHCHLDAHVP MGLGMVFAVD NGTTPDSFLP

PPPADLPKC
Length:559
Mass (Da):60,212
Last modified:February 1, 2005 - v1
Checksum:iE39123EF1389DDE0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003242 Genomic DNA. Translation: BAD81779.1.
AP004072 Genomic DNA. Translation: BAD82647.1.
AP008207 Genomic DNA. Translation: BAF06729.1.
AP014957 Genomic DNA. Translation: BAS75243.1.
CM000138 Genomic DNA. Translation: EEE55677.1.
AK109431 mRNA. Translation: BAG98743.1.
RefSeqiXP_015621472.1. XM_015765986.1.
UniGeneiOs.14830.

Genome annotation databases

EnsemblPlantsiOS01T0850700-02; OS01T0850700-02; OS01G0850700.
GeneIDi4324802.
GrameneiOS01T0850700-02; OS01T0850700-02; OS01G0850700.
KEGGiosa:4324802.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003242 Genomic DNA. Translation: BAD81779.1.
AP004072 Genomic DNA. Translation: BAD82647.1.
AP008207 Genomic DNA. Translation: BAF06729.1.
AP014957 Genomic DNA. Translation: BAS75243.1.
CM000138 Genomic DNA. Translation: EEE55677.1.
AK109431 mRNA. Translation: BAG98743.1.
RefSeqiXP_015621472.1. XM_015765986.1.
UniGeneiOs.14830.

3D structure databases

ProteinModelPortaliQ5N7B4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os01g63190.1.

Proteomic databases

PaxDbiQ5N7B4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS01T0850700-02; OS01T0850700-02; OS01G0850700.
GeneIDi4324802.
GrameneiOS01T0850700-02; OS01T0850700-02; OS01G0850700.
KEGGiosa:4324802.

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ5N7B4.
OMAiIVHYNTT.
OrthoDBiEOG093605KG.

Gene expression databases

ExpressionAtlasiQ5N7B4. baseline and differential.
GenevisibleiQ5N7B4. OS.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLAC7_ORYSJ
AccessioniPrimary (citable) accession number: Q5N7B4
Secondary accession number(s): A2ZZL5, B7F296
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: February 1, 2005
Last modified: October 5, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.