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Protein

Laccase-6

Gene

LAC6

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi82Copper 1By similarity1
Metal bindingi84Copper 2By similarity1
Metal bindingi127Copper 2By similarity1
Metal bindingi129Copper 3By similarity1
Metal bindingi480Copper 4By similarity1
Metal bindingi483Copper 1By similarity1
Metal bindingi485Copper 3By similarity1
Metal bindingi543Copper 3By similarity1
Metal bindingi544Copper 4By similarity1
Metal bindingi545Copper 2By similarity1
Metal bindingi549Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processLignin degradation
LigandCopper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-6 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 6
Diphenol oxidase 6
Urishiol oxidase 6
Gene namesi
Name:LAC6
Ordered Locus Names:Os01g0850550, LOC_Os01g63180
ORF Names:OsJ_003986, P0529H11.21
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000029189123 – 580Laccase-6Add BLAST558

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi44N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi78N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi306N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi335N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi385N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi397N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi462N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ5N7A3

Expressioni

Gene expression databases

ExpressionAtlasiQ5N7A3 differential
GenevisibleiQ5N7A3 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g63180.1

Structurei

3D structure databases

ProteinModelPortaliQ5N7A3
SMRiQ5N7A3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 148Plastocyanin-like 1Add BLAST119
Domaini158 – 317Plastocyanin-like 2Add BLAST160
Domaini424 – 564Plastocyanin-like 3Add BLAST141

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263 Eukaryota
COG2132 LUCA
InParanoidiQ5N7A3
KOiK05909
OMAiQMRNTVG
OrthoDBiEOG093605LR

Family and domain databases

CDDicd13849 CuRO_1_LCC_plant, 1 hit
cd13875 CuRO_2_LCC_plant, 1 hit
Gene3Di2.60.40.420, 3 hits
InterProiView protein in InterPro
IPR001117 Cu-oxidase
IPR011706 Cu-oxidase_2
IPR011707 Cu-oxidase_3
IPR033138 Cu_oxidase_CS
IPR002355 Cu_oxidase_Cu_BS
IPR008972 Cupredoxin
IPR034288 CuRO_1_LCC
IPR034285 CuRO_2_LCC
IPR017761 Laccase
PfamiView protein in Pfam
PF00394 Cu-oxidase, 1 hit
PF07731 Cu-oxidase_2, 1 hit
PF07732 Cu-oxidase_3, 1 hit
SUPFAMiSSF49503 SSF49503, 4 hits
TIGRFAMsiTIGR03389 laccase, 1 hit
PROSITEiView protein in PROSITE
PS00079 MULTICOPPER_OXIDASE1, 1 hit
PS00080 MULTICOPPER_OXIDASE2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5N7A3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCSWMIPVF AILAFVASAA QADVVEHTFN VATLSLPRIC QPGNTSVTAV
60 70 80 90 100
NGRVPGPQVE AREGDTVVIH VINDSPYNVT VHWHGVFQRG TPWADGPAMV
110 120 130 140 150
TQCPIRPGHR YTYRFAVAGQ EGTLWWHAHS SYMRATVYGA LVIRPRRAGG
160 170 180 190 200
YPFPTPYEEK TVLLGEWWNG DPVALESQSF STGIPAPNAD AYTINGMPGD
210 220 230 240 250
SYLCPETTNR IAKFEVRRDK TYLLRIINAA LNTAFFFKVA GHTFTVVAAD
260 270 280 290 300
ASYTEPYATD VIVIAPGQTV DALMAADASP GCYHMAISSY QSAIPFPPRP
310 320 330 340 350
AGFNGNTSTA IVEYVDATAT TDAGSPVLPV MPKPNDTYTA NQFYTSLTAL
360 370 380 390 400
IRPGRRTVPL TVDTRMLVTV GLGFSSCQPE QTQCNRSAPV VLANMNNVSF
410 420 430 440 450
ALPNTVSMLE ALYRNTADGV YTRDFPDQPP VAFDYTSRGL LGNSPLASTG
460 470 480 490 500
SPSTKVKTLR YNATVEMVLQ NTALVGLESH PMHLHGFNFF VVAQGFGNND
510 520 530 540 550
GEAAGAGEFN LVNPQERNTV AVPTGGWAVI RFVADNPGMW AMHCHIDSHF
560 570 580
AIGLAMVFEV ESGPTPGTTL PPPPPDLPQC
Length:580
Mass (Da):62,569
Last modified:February 1, 2005 - v1
Checksum:iC920CD4B9452D017
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003242 Genomic DNA Translation: BAD81778.1
AP004072 Genomic DNA Translation: BAD82646.1
AP014957 Genomic DNA Translation: BAS75242.1
CM000138 Genomic DNA No translation available.
RefSeqiXP_015621471.1, XM_015765985.1

Genome annotation databases

EnsemblPlantsiOs01t0850550-00; Os01t0850550-00; Os01g0850550
GeneIDi107276446
GrameneiOs01t0850550-00; Os01t0850550-00; Os01g0850550
KEGGiosa:107276446

Similar proteinsi

Entry informationi

Entry nameiLAC6_ORYSJ
AccessioniPrimary (citable) accession number: Q5N7A3
Secondary accession number(s): A0A0P0VAL3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: February 1, 2005
Last modified: May 23, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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