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Q5N643 (SYR_SYNP6) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:syc0034_c
OrganismSynechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) [Complete proteome] [HAMAP]
Taxonomic identifier269084 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length584 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 584584Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242108

Regions

Motif126 – 13611"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q5N643 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: A8591A4497FC4999

FASTA58465,082
        10         20         30         40         50         60 
MAAPLAQLRD RFQAALAASF GPEWAATDPL LVPATNPKFG DYQSNVAMSL AKQLGQPPRA 

        70         80         90        100        110        120 
IAETLVQNLN LADLCEPPAI AGPGFINFTL QPSYLVAQLQ QLQTDERLGI QPVSPPQRVI 

       130        140        150        160        170        180 
VDFSSPNIAK EMHVGHLRST IIGDSIARVL EFQGHEVLRL NHVGDWGTQF GMLIAFLQEQ 

       190        200        210        220        230        240 
YPQALSQPDA LDISDLVAFY KQAKARFDED PSFQETARQR VVDLQSGEAT ARQAWQLLCD 

       250        260        270        280        290        300 
QSRREFQKIY DRLDIQLEER GESFYNPYLP AIVEDLRRLG LLVEDQGAQC VFLEGFQNKE 

       310        320        330        340        350        360 
GQPLPLIVQK SDGGYNYATT DLAALRYRLG QDQAQRIIYV TDSGQANHFA QVFQVAQRAG 

       370        380        390        400        410        420 
WLPAAAQIEH VPFGLVQGED GKKLKTRAGD TVRLRDLLDE AVDRARTDLT TRIAAEERSE 

       430        440        450        460        470        480 
TPEFIEAVAQ AVGLGAVKYA DLSQNRNSNY IFSFDKMLAL QGNTAPYLLY AYVRIQGIAR 

       490        500        510        520        530        540 
KGGIDFAQLD PVAAELTEPT ERSLAKQVLQ LGEVLDEVAR DLLPNRLCSY LFELSQTFNQ 

       550        560        570        580 
FYDRCPILNA EEPQRTSRLL LCDLTARTLK LGLSLLGISV LERM 

« Hide

References

[1]"Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization."
Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M., Kanehisa M., Omata T., Sugiura M., Sugita M.
Photosyn. Res. 93:55-67(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27144 / PCC 6301 / SAUG 1402/1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008231 Genomic DNA. Translation: BAD78224.1.
RefSeqYP_170744.1. NC_006576.1.

3D structure databases

ProteinModelPortalQ5N643.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING269084.syc0034_c.

Proteomic databases

PRIDEQ5N643.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD78224; BAD78224; syc0034_c.
GeneID3198294.
KEGGsyc:syc0034_c.
PATRIC32485532. VBISynElo117686_0046.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycSELO269084:GCDQ-36-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_SYNP6
AccessionPrimary (citable) accession number: Q5N643
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: February 1, 2005
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries